D-Fructose

Drug ingredient

CAS 57-48-7

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$143M

Import volume33.1K lb

Top sourceMexico 69%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.

Where It Comes From

Customs basis: HS 170250, 170260 · exact

EPA reports by year

2023: US production Confidential · Imports 33.1K lb
2019: US production Confidential · Imports Zero

Source Countries

Country of origin for US imports, from Census customs data (2024).

MX 69%MexicoCA 14%CanadaTW 5%TaiwanTR 3%TurkeyPK 2%Pakistan

South Korea
Belgium
Netherlands
Slovakia
Finland
Malaysia
Italy
Slovenia
Sri Lanka
Greece
United Kingdom
Germany
India
Peru
Vietnam
Bangladesh
Lebanon
Iraq
Japan
Egypt
Portugal
Brazil
Australia
Armenia

EPA-registered manufacturers (4)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Archer Daniels Midland

Cargill, Incorporated

Primary Products Ingredients Americas

Roquette America

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Brenntag

EPA-registered importers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

The Scotts

Why It Matters

Sectors

HealthAgriculture

Downstream Uses

Appears in 18 drug and cosmetic product listings (FDA).

•Anti Nausea Liquid Cherry Flavor
•Emetrol Cherry
•Emetrol Children Mixed Berry
•Glucose Drops 2031
•Best Choice Anti Nausea Cherry Flavor
•Premier Value Nausea Control Cherry Flavor
•Anti Nausea
•HEB Anti Nausea

Show all 18

•Walgreen Anti Nausea Cherry Flavor
•Good Neighbor Anti Nausea Cherry Flavor
•Quality Choice Anti-Nausea
•CVS Anti Nausea Cherry Flavor
•Walgreen Children ANTI Nausea
•Anti Nausea Liquid
•Meijer Anti Nausea
•Discount Drug Mart nausea control Cherry Flavor
•Sugar Cravings
•Kroger Anti Nausea Cherry Flavor

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Soil amendments (fertilizers) in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (100%)Processing—repackaging

Chemical Identity

CAS57-48-7

PubChem CID2723872

DTXSIDDTXSID5023081

FormulaC6H12O6

Mol. Weight180.16 g/mol

SMILESC1C(C(C(C(O1)(CO)O)O)O)O

Data Sources

EPA CompTox (DSSTox) · DTXSID5023081Retrieved 2026-04-06
PubChem · compound 2723872Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

D-Fructose (CAS 57-48-7) https://chemicalindependence.com/chemical/57-48-7/ EPA CompTox (DSSTox): DTXSID5023081. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID5023081 PubChem: 2723872. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/2723872 EPA Chemical Data Reporting: 57-48-7. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 170250,170260 for CAS 57-48-7. Reporting year: 2024. https://usatrade.census.gov/