Physostigmine

CAS 57-47-6

Pyrrolo[2,3-b]indol-5-ol, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-, 5-(N-methylcarbamate), (3aS,8aR)-

Molecular structure of 57-47-6
US productionNot reported
Import value, 2024$171M
Top sourceSwitzerland 40%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293979 · basket

These shares come from HS customs code 293979, which covers 60 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CH 40%SwitzerlandCN 18%ChinaIT 14%ItalyDE 13%GermanyIN 10%India

Why It Matters

No EPA sector or FDA product records name a use for this chemical.

Vendor Pricing

$453.00/gLabotest KG
CountryGermany
Pack$453.00 / 1000 mg
Purity90%
Vendors10 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS57-47-6
PubChem CIDNot recorded
DTXSIDDTXSID3023471
FormulaC15H21N3O2
Mol. Weight275.352 g/mol
SMILESCNC(=O)OC1=CC2=C(C=C1)N(C)[C@H]1N(C)CC[C@@]21C

Data Sources

Brief citations

Physostigmine (CAS 57-47-6) https://chemicalindependence.com/chemical/57-47-6/ EPA TSCA Inventory: CAS 57-47-6. Retrieved 2026-10-04. https://www.epa.gov/tsca-inventory US Census international trade: HS 293979 for CAS 57-47-6. Reporting year: 2024. https://usatrade.census.gov/