Urea
Drug ingredientCAS 57-13-6
This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$1.7B
Top sourceRussia 23%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.
Where It Comes From
Customs basis: HS 310210 · exact
EPA reports by year
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
Source Countries
Country of origin for US imports, from Census customs data (2024).
RU 23%RussiaQA 20%QatarCA 14%CanadaDZ 9%AlgeriaSA 9%Saudi Arabia
- Brunei
- Japan
- Azerbaijan
- China
- Spain
- Mexico
- Albania
- India
- Dominican Republic
- Australia
- Vietnam
- Italy
- Switzerland
- Poland
- Brazil
- Ukraine
- South Korea
- Bahrain
- Denmark
- Belgium
- Israel
EPA-registered manufacturers (20)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Incitec Pivot · AU Australia
Marubeni · JP Japan
Nutrien · CA Canada
Oci N V · NL Netherlands
Advanced Micronutrient Products
Show all 20
Cf Industries
Cornerstone Chemical
Cvr Energy
Dakota Gasification
Dynachem
Dyno Nobel St. Helens
Eli Lilly And
Hawkins
Iowa Intermediate Fertilizer Holding
J.R. Simplot
Koch Industries
Lsb Industries
Macrosource
Nutrien Us Top
Tri-Chem Industries
Domestic parents -- activity not disclosed (12)
EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.
Icl Specialty Products North America
International Raw Materials
Nitron Group
Old World Industries
Polyventive
Show all 12
Snf Holding
Sojitz Corporation Of America
Solvay
Teck American Incorporated
The Mosaic
Valudor Products
Willert Home Products
EPA-registered importers (36)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Archroma Management Gmbh · CH Switzerland
Azelis S A · LU Luxembourg
Basf Se · DE Germany
Eurochem Group Ag · CH Switzerland
Irving Oil · CA Canada
Show all 36
Marubeni · JP Japan
Master Plant-Prod · CA Canada
Mercedes-Benz Group Ag · DE Germany
Nexteer Automotive Group · KY Cayman Islands
Sociedad Quimica Y Minera S A · CL Chile
Sojitz · JP Japan
Archer Daniels Midland
Archroma U.S
Azelis Us Holdings
Basf
Brenntag Lubricants
Chevron Phillips Chemical
Chs
Dte Energy
Eurochem North America
Haifa North America
Helm America
Irving Oil Energy
Kemira Water Solutions
Livingston International
Mercedes-Benz Vans
Nutrien Us
Packaging Corporation Of America
Pcm Us Steering Holding
Recochem
Ricoh Usa
Sqm North America
Tannin
The Chemical
Valagro/Syngenta Biologicals
Wintersun International
23 FDA-registered drug labelers
AKRON PHARMA INC
Aloe Vera Korea Co.,Ltd.
AvPAK
Bantry Pharma, LLC
Bestmade Natural Products
BioComp Pharma, Inc.
Blue Heron Pharmaceuticals, LLC
Bryant Ranch Prepack
Cintex Services, LLC
Corden Pharma GmbH
Fagron Inc
Guangdong Junhui Biotechnology Co.,LTD
Jiangxi Yudexi Pharmaceutical Co., LTD
Laser Pharmaceuticals, LLC
Merck KGaA
Method Pharmaceuticals, LLC
Oncora Pharma, LLC
Patrin Pharma, Inc
Professional Complementary Health Formulas
Professional Compounding Centers of America
PureTek Corporation
Shenzhen Ishan Technology Co., Ltd
Spectrum Laboratory Products, Inc.
Why It Matters
Sectors
FoodPlastics & RubberPaints & CoatingsTransportationPaper & PrintingCore ChemicalsHealthEnergyConsumer ProductsMetals & MiningWaterTextilesAgricultureConstruction
Downstream Uses
Appears in 21 drug and cosmetic product listings (FDA).
- •iShanCare Cracked Skin Cream
- •Urea Cream 41%
- •Urea 39% Cream
- •Urea 20
- •Urea Cream 40 Percent
- •Bestmade Natural Products BM64
- •AOAO Repair Foot Cream
- •Dermacure
Show all 21
- •Uredex
- •UREA
- •Uracin 20%
- •Miracle FootCream Lavender
- •Healmusz Healthy FEET
- •Urea Cream 40%
- •Urea 40 Percent
- •Pancreas Drops 5020
- •Miracle FootCream Lemon
- •Urea 40%
- •Urea 41%
- •Urea 39.5%
- •Urea 39.5% with 2% Salicylic Acid
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
Used in 26 sectors as 25 functional roles.
- •Humectant in Printing Ink ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Reducing agent in Utilities (1%)Processing—incorporation into formulation, mixture, or reaction product
- •pH regulating agent in All Other Chemical Product and Preparation Manufacturing (10%)Processing as a reactant
- •Soil amendments (fertilizers) in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (0%)Processing—repackaging
- •pH regulating agent in Pharmaceutical and Medicine Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in All Other Basic Organic Chemical Manufacturing (0%)Processing as a reactant
- •Flame retardant in All Other Chemical Product and Preparation Manufacturing (0%)Processing as a reactant
- •Impregnation agent in All Other Basic Organic Chemical Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in All Other Chemical Product and Preparation Manufacturing (1%)Processing as a reactant
- •Impregnation agent in Wood Product Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Adhesion/cohesion promoter in Adhesive Manufacturing (0%)Processing as a reactant
- •Reducing agent in All Other Chemical Product and Preparation Manufacturing (30%)Processing—incorporation into formulation, mixture, or reaction product
- •Soil amendments (fertilizers) in OtherProcessing—repackaging
- •Processing aids, specific to petroleum production in Oil and Gas Drilling, Extraction, and Support activities (100%)Use—non-incorporative activities
- •Fuel agents in Petroleum Refineries (0%)Processing—repackaging
- •Soil amendments (fertilizers) in Agriculture, Forestry, Fishing and Hunting (100%)Use—non-incorporative activities
- •Soil amendments (fertilizers) in Wholesale and Retail Trade (100%)Processing—repackaging
- •Fuel agents in All Other Basic Organic Chemical Manufacturing (13%)Processing—repackaging
- •Reducing agent in All Other Basic Inorganic Chemical Manufacturing (23%)Processing—incorporation into formulation, mixture, or reaction product
- •Adhesion/cohesion promoter in Plastics Material and Resin Manufacturing (21%)Processing—repackaging
- •Soil amendments (fertilizers) in All Other Basic Inorganic Chemical Manufacturing (52%)Processing—repackaging
- •Absorbent in UtilitiesProcessing—incorporation into formulation, mixture, or reaction product
- •Lubricating agent in Transportation Equipment Manufacturing (100%)Processing—incorporation into article
- •Chemical reaction regulator in All Other Chemical Product and Preparation Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Pharmaceutical and Medicine Manufacturing (2%)Use—non-incorporative activities
- •Fuel agents in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (1%)Processing as a reactant
- •Intermediate in Plastics Material and Resin ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Reducing agent in Other (80%)Processing as a reactant
- •Fuel agents in Wholesale and Retail Trade (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Softener and conditioner in Textiles, apparel, and leather manufacturing (100%)Processing—incorporation into article
- •Binder in Wood Product Manufacturing (5%)Processing as a reactant
- •Reducing agent in Wood Product Manufacturing (3%)Processing as a reactant
- •Diluent in Wholesale and Retail Trade (100%)Not Known or Reasonably Ascertainable
- •CBI in CBICBI
- •Fuel agents in All Other Chemical Product and Preparation Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Lubricating agent in Wholesale and Retail TradeProcessing—incorporation into formulation, mixture, or reaction product
- •Monomers in Synthetic Dye and Pigment Manufacturing (100%)Processing as a reactant
- •Fuel agents in Other (5%)Processing—incorporation into formulation, mixture, or reaction product
- •Fuel agents in Utilities (2%)Processing as a reactant
- •Fuel agents in Miscellaneous Manufacturing (1%)Processing as a reactant
- •Dye in Paper Manufacturing (28%)Processing—incorporation into article
- •Flocculating agent in Utilities (56%)Use—non-incorporative activities
- •Chemical reaction regulator in Transportation Equipment Manufacturing (100%)Use—non-incorporative activities
- •Solids separation (precipitating) agent, not otherwise specified in All Other Basic Organic Chemical Manufacturing (2%)Processing—repackaging
- •Solids separation (precipitating) agent, not otherwise specified in Food, beverage, and tobacco product manufacturing (10%)Use—non-incorporative activities
- •Solids separation (precipitating) agent, not otherwise specified in Mining (except Oil and Gas) and support activities (20%)Use—non-incorporative activities
- •Solids separation (precipitating) agent, not otherwise specified in Utilities (40%)Use—non-incorporative activities
- •Solids separation (precipitating) agent, not otherwise specified in Fabricated Metal Product Manufacturing (20%)Use—non-incorporative activities
- •Freeze-thaw additive in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Binder in Paint and Coating ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Waterproofing agent in Paint and Coating ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (100%)Processing as a reactant
- •Solvent in Printing and Related Support Activities (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Thickening agent in Wholesale and Retail TradeNot Known or Reasonably Ascertainable
Vendor Pricing
$0.01/gA2B Chem LLC
CountryUnited States
Pack$99.00 / 10 kg
Purity99%
Vendors20 available
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
19 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| Sigma-Aldrich (Rush Stock) | Germany | $0.01 | 20 kg | 100.5% |
| Sigma-Aldrich | Germany | $0.01 | 20 kg | 100.5% |
| AA BLOCKS | United States | $0.01 | 10 kg | 99% |
| Fluorochem UK | United Kingdom | $0.03 | 5 kg | 99% |
| ALFA AESAR | Germany | $0.04 | 2.5 kg | 99.3% |
| Fluorochem EU | Germany | $0.04 | 1 kg | 99% |
| AK Scientific Specialized | United States | $0.04 | 1 kg | 98% |
| Apollo Scientific US | United Kingdom | $0.06 | 5 kg | 99.5% |
| AK Scientific, Inc. | United States | $0.07 | 1 kg | 99% |
| Apexbio Technology LLC | United States | $0.12 | 1 kg | 98% |
| Combi-Blocks, Inc. | United States | $0.25 | 1 kg | 98% |
| AstaTech, Inc | United States | $1.12 | 25 g | 95% |
| MedChemExpress MCE | Sweden | $17.42 | 5 g | 99.84% |
| Labotest KG | Germany | $217.80 | 5000 mg | 90% |
| Molnova | China | $380.00 | 100 mg | 99% |
| TargetMol Chemicals | China → United States | $420.00 | 100 mg | 99.44% |
| Princeton BioMolecular Research (SC) | United States | $2900.00 | 100 mg | 90% |
| Vitas M Chemical Limited | Hong Kong | $3170.00 | 100 mg | 90% |
| Key Organics Ltd. | United Kingdom | $6900.00 | 10 mg | 95% |
Chemical Identity
CAS57-13-6
PubChem CID1176
DTXSIDDTXSID4021426
FormulaCH4N2O
Mol. Weight60.056 g/mol
SMILESC(=O)(N)N
Data Sources
- EPA CompTox (DSSTox) · DTXSID4021426Retrieved 2026-04-06
- PubChem · compound 1176Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- FDA National Drug Code directoryRetrieved 2026-04-07
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Urea (CAS 57-13-6) https://chemicalindependence.com/chemical/57-13-6/ EPA CompTox (DSSTox): DTXSID4021426. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID4021426 PubChem: 1176. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/1176 EPA Chemical Data Reporting: 57-13-6. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 57-13-6. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 310210 for CAS 57-13-6. Reporting year: 2024. https://usatrade.census.gov/