Creatine

Drug ingredient

CAS 57-00-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 57-00-1
US productionNot reported
Import value, 2024$240M
Top sourceChina 37%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292529 · basket

These shares come from HS customs code 292529, which covers 64 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 37%ChinaDE 19%GermanyES 9%SpainIT 8%ItalyID 8%Indonesia
3 FDA-registered drug labelers
BioActive Nutritional, Inc.
Energique, Inc.
Professional Complementary Health Formulas

Why It Matters

Sectors
Health
Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

  • •Colotox
  • •Recovatone
  • •Energy Regulation Combination 9308
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$0.04/gAaron Chemicals LLC
CountryHong Kong
Pack$21.00 / 500 g
Purity99%
Vendors33 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS57-00-1
PubChem CID586
DTXSIDDTXSID1040451
FormulaC4H9N3O2
Mol. Weight131.13 g/mol
SMILESCN(CC(=O)O)C(=N)N

Data Sources

Brief citations

Creatine (CAS 57-00-1) https://chemicalindependence.com/chemical/57-00-1/ PubChem: 586. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/586 EPA TSCA Inventory: CAS 57-00-1. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292529 for CAS 57-00-1. Reporting year: 2024. https://usatrade.census.gov/