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meclizine hydrochloride

Drug ingredient

CAS 569-65-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 569-65-3
2 HCl · 1 H₂O
US productionNot reported
Import value, 2024$7.6B
Top sourceIreland 61%

EPA lists this chemical as inactive, meaning no company reported making, importing or processing it in the US from 2006 to 2016.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293359 · basket

These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India
84 FDA-registered drug labelers
A-S Medication Solutions
Acme United Corporation
Advance Pharmaceutical Inc.
Advanced Rx LLC
Advanced Rx of Tennessee, LLC
American Health Packaging
Amerisource Bergen
Amneal Pharmaceuticals LLC
Amneal Pharmaceuticals of New York LLC
Aphena Pharma Solutions - Tennessee, LLC
APNAR PHARMA LP
ARMY AND AIR FORCE EXCHANGE SERVICE
Asclemed USA, Inc.
Aurobindo Pharma Limited
AvPAK
Better Living Brands, LLC
Bi-Mart
BluePoint Laboratories
Bryant Ranch Prepack
Calyx Chemicals & Pharmaceuticals
Cardinal Health 110, LLC. DBA Leader
CHAIN DRUG MARKETING ASSOCIATION INC
Chartwell RX, LLC
COHANCE LIFESCIENCES LIMITED
CVS PHARMACY, INC.
CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED
DirectRx
DOLGENCORP, LLC
Epic Pharma LLC
Family Dollar Services Inc
Geri-Care Pharmaceutical Corp
H E B
JC World Bell Wholesale Co., Inc.
Jubilant Biosys limited
Jubilant Cadista Pharmacuticals Inc.
Kroger Company
L.N.K. International, Inc.
Lil' Drug Store Products, Inc.
Lydia Co., Ltd.
Major Pharmaceuticals
Medtech Products Inc.
Meijer Distribution Inc
Navajo Manufacturing Company Inc.
NCS HealthCare of KY, LLC dba Vangard Labs
Northwind Health Company, LLC
NuCare Pharmaceuticals, Inc.
PD-Rx Pharmaceuticals, Inc.
Pharbest Pharmaceuticals, Inc.
Preferred Pharmaceuticals Inc.
Proficient Rx LP
PuraCap Pharmaceutical LLC
QPharma Inc
Redpharm Drug
Reliable 1 Laboratories LLC
REMEDYREPACK INC.
Richmond Pharmaceuticals, Inc.
Rising Pharma Holdings, Inc.
Rite Aid Corporation
RUGBY LABORATORIES
Salado Sales, Inc.
Sato Pharmaceutical Co., LTD
Shield Pharmaceuticals Corp
Spectrum Laboratory Products, Inc.
Sportpharm LLC
Sri Krishna Pharmaceuticals Ltd. Unit I
St. Mary's Medical Park Pharmacy
Strategic Sourcing Services LLC
Symed Labs Limited
TARGET CORPORATION
THE PROCTER & GAMBLE MANUFACTURING COMPANY
THINQ Pharma-CRO Limited
Time-Cap Labs, Inc
Topco Associates, LLC
Ulai Health LLC
Unifirst First Aid Corporation
United Natural Foods, Inc. dba UNFI
Wal-Mart Stores Inc
Walgreen Co.
Walgreen Company
WALMART INC.
WellSpring Pharmaceutical Corporation
Xenex Laboratories Inc
Zydus Lifesciences Limited
Zydus Pharmaceuticals (USA) Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 28 drug and cosmetic product listings (FDA).

  • •Meclizine Hydrochloride
  • •Meclizine
  • •Motion Sickness
  • •ZenTrip Motion Sickness
  • •Dramamine
  • •Motion Sickness Relief
  • •Nausea Relief
  • •Motion Sickness Relief Less Drowsy
Show all 28
  • •Motion-Time Chewable
  • •Bonine
  • •Dramamine Less Drowsy
  • •Meclizine HCl
  • •Wal-Dram 2 Quick-Dissolving
  • •PhysiciansCare Motion Sickness
  • •Dramamine Less Drowsy Meclizine Hydrochloride
  • •Meclizine HCL 25 mg
  • •Meclizine HCL 12.5 mg
  • •Less Drowsy Formula Motion Sickness Relief
  • •Pepto Nausea Motion Sickness
  • •Meclizine Hydrocloride
  • •Medique Medi-Meclizine
  • •Travel-Ease
  • •CVS Motion Sickness Fast Melting
  • •Novominsyrup
  • •Less Drowsy Motion Sickness Relief
  • •Dramamine Less Drowsy, Lil Drug Store
  • •Dramamine - N
  • •Bonine MAX
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS569-65-3
PubChem CID173612
DTXSIDDTXSID0023242
FormulaC25H31Cl3N2O
Mol. Weight481.9 g/mol
SMILESCC1=CC(=CC=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl.O.Cl.Cl

Data Sources

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Brief citations

meclizine hydrochloride (CAS 569-65-3) https://chemicalindependence.com/chemical/569-65-3/ PubChem: 173612. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/173612 EPA TSCA Inventory: CAS 569-65-3. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293359 for CAS 569-65-3. Reporting year: 2024. https://usatrade.census.gov/