trimethoprim sulfate

Drug ingredient

CAS 56585-33-2

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$7.6B

Top sourceIreland 61%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293359 · basket

These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India

Israel
Bulgaria
Japan
Spain
Sweden
Canada
Taiwan
Finland
Portugal
Mexico
Belgium
Hungary
Austria
Brazil
Ukraine
Croatia
Malta
South Korea
South Africa
Denmark
Czech Republic
Malaysia
Argentina
Poland
Cameroon
Australia
Hong Kong
Slovakia
Latvia

9 FDA-registered drug labelers

A-S Medication Solutions

Bausch & Lomb Incorporated

NuCare Pharmaceuticals,Inc.

Preferred Pharmacetucials Inc.

Preferred Pharmaceuticals Inc.

Proficient Rx LP

REMEDYREPACK INC.

Sandoz Inc

Sportpharm LLC

Why It Matters

Sectors

Health

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•Polymyxin B Sulfate and Trimethoprim
•Trimethoprim sulfate and Polymyxin B sulfate

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$625.00/gMedKoo Biosciences, Inc

CountryUnited States

Pack$1250.00 / 2 g

Purity98%

Vendors1 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS56585-33-2

PubChem CID64936

DTXSIDDTXSID40205138

FormulaC28H38N8O10S

Mol. Weight678.7 g/mol

SMILESCOC1=CC(=CC(=C1OC)OC)CC2=CN=C(N=C2N)N.COC1=CC(=CC(=C1OC)OC)CC2=CN=C(N=C2N)N.OS(=O)(=O)O

Data Sources

PubChem · compound 64936Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

trimethoprim sulfate (CAS 56585-33-2) https://chemicalindependence.com/chemical/56585-33-2/ PubChem: 64936. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/64936 FDA National Drug Code directory: CAS 56585-33-2. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293359 for CAS 56585-33-2. Reporting year: 2024. https://usatrade.census.gov/