Glycerol
Drug ingredientCAS 56-81-5
This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$159M
Top sourceIndonesia 41%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.
Where It Comes From
Customs basis: HS 152000, 290545 · exact
EPA reports by year
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
Source Countries
Country of origin for US imports, from Census customs data (2024).
ID 41%IndonesiaMY 19%MalaysiaCA 12%CanadaIN 11%IndiaDE 11%Germany
- Netherlands
- Japan
- China
- Pakistan
- Philippines
- Belgium
- Taiwan
- Mexico
- Colombia
- Peru
- Switzerland
- United Kingdom
- Ireland
- Israel
- Singapore
- Chile
- Australia
- Jamaica
- Spain
- Bulgaria
EPA-registered manufacturers (32)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Basf Se · DE Germany
Indorama Netherlands Bv · NL Netherlands
Syensqo Sa · BE Belgium
Adkins Energy
Ag Processing
Show all 32
American Greenfuels
Archer Daniels Midland
Baker Commodities
Basf
Cargill, Incorporated
Chevron
Coast Southwest
Delek Us Holdings
Futurefuel
Hartree Partners
Imperial Western Products
Indorama Ventures Usa Holdings
Iowa Renewable Energy
Jtm Products
Lake Erie Biofuels
Lake Erie Biofuels, Llc Dba Hero Bx
Louis Dreyfus Agricultural Industries Ll, In
Minnesota Soybean Processors
Nalco- An Ecolab
P&G
Pmc Biogenix
Rbf Port Neches
Solvay
Starchem
Vanderbilt Chemicals
Verdant Specialty Solutions
Western Iowa Energy
Domestic parents -- activity not disclosed (22)
EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.
A.G. Layne
Advance Research Chemicals
Azelis Us Holding
Brenntag
Buckman Laboratories
Show all 22
Cellmark Basic Materials
Emery Oleochemicals
Flint Cps Inks North America
Hexion
International Flavors And Fragrances
Kensing
Marathon Petroleum
Marubeni America
Mccullough & Associates
Norman, Fox &
Olin
Polymer Additves
Polyventive
Rierden Chemical & Trading
Solvchem
Stepan
Vantage Specialty Chemicals
EPA-registered importers (44)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Basf Se · DE Germany
Brenntag · DE Germany
Dr Ing H C F Porsche Ag · DE Germany
Ioi Acidchem Sdn Bhd · MY Malaysia
Kcc · KR South Korea
Show all 44
Kh Chemicals International B V · NL Netherlands
Ravago S A · LU Luxembourg
Reckitt Benckiser Group · GB United Kingdom
Syensqo Sa · BE Belgium
Acidchem (Usa)
Acme-Hardesty Co A Division Of Jacob Stern & Sons
Ambyth Chemical
Blue Tree Holdings
Brother International
Canon U.S.A
Cht Usa
Colonial Group
Daxx
Delta Carbona
Dollar General Cdr
Dow Chemical
Greenchem Industries
Gsd Distribution
Hallmark Cards
Hilti
Honeywell International (123312)
Hp
Icof America
Kg International
Kh Chemicals Na
Mom Holding
Oleon Americas
Phibro Animal Health
Porsche Cars North America
Reckitt Benckiser
S.C. Johnson & Son
Silver Fern Chemical
Solenis
Soyventis North America
Stratasys
Tannin
Target
Transchem
Wintersun International
Why It Matters
Sectors
HealthAgricultureFoodEnergyConstructionMetals & MiningPlastics & RubberTextilesConsumer ProductsPaints & CoatingsPaper & PrintingCore Chemicals
Downstream Uses
Appears in 256 drug and cosmetic product listings (FDA).
- •DCH Hemorrhoidal
- •Revivol Hemorrhoid and Fissure
- •Optase
- •Optimel Manuka Forte Eye Gel
- •AN12 ANUS Premium Cleanser
- •AN12 Skin Therapy Vita-B Aloe Soothing Gel
- •Anubis Barcelona Regul Oil
- •Anubismed
Show all 256
- •Moisturize Cream
- •Naughty Kitty Kat
- •Sting Relief prep Pad
- •Regener-Eyes Ophthalmic Solution Professional Strength XL
- •Regener-Eyes Ophthalmic Solution Professional
- •meijer Maximum Strength Sore Throat Fast Relief
- •Oasis Tears Lubricant Eye
- •ThroatSpray
- •Chemstat
- •Colirio Ojo De Aguila Eye Drops
- •Refresh Tears PF
- •Refresh Optive
- •Discount Drug Mart Eye Drops Dry Eye Relief
- •Refresh Relieva PF Xtra
- •DG Health Dry Eye Relief
- •CVS Pharmacy Glycerin Laxative
- •Clenziderm Therapeutic Moisturizer
- •Brain Enhancement Liquescence 3006
- •Libido Stim Liquescence 3014
- •Glycerin
- •Clear Eyes Maximum Itchy Eye Relief
- •Durma DynaGel
- •Leader Eye Drops Redness Relief
- •Leader Dry Eye Relief Eye Drops
- •FIND Bichon Cleansing MASK
- •CareOne Maximum Redness Relief Eye Drops
- •Optimel Manuka Dry Eye Drops
- •Gaezoa Cream
- •Preparation H Rapid Relief
- •Maximum Strength Hemorrhoidal Cream with Aloe
- •Bee Venom Joint Cream
- •Atti amour Rose Anti-Aging Repair Eye Cream
- •Optiq Hydrate
- •Milia remover treatment
- •Regener-Eyes Ophthalmic Solution LITE XL
- •Regener-Eyes Ophthalmic Solution LITE
- •Target Eye Drops Maximum Redness Relief Eye
- •Rite-Aid Glycerin Laxative
- •Biotrue Hydration Boost
- •Pedia-Lax
- •Oasis Tears PF Preservative-Free Lubricant Eye
- •Refresh Optive Mega-3
- •Refresh Optive Advanced
- •Stratuscare Glycerin Laxative Pediatric
- •Hemorrhoidal Cream
- •Curist Hemorrhoid Fissure Relief
- •Zenibell Snail Intensive
- •aewajin Derma Hydrocell 24k Gold Serum
- •Preparation H Maximum Strength
- •Miracle FootCream Lavender
- •Regener-Eyes PRO
- •Anubis Barcelona
- •MegaBabe Butt Stuff Hemorrhoidal
- •Hydropure Lubricating Eye Drops
- •Sukkhi Polyamino Sugar Condensate Massage Cream
- •iq shield pro 60g goat milk silk
- •Cureforte Breath Reset
- •WowDay Hemorrhoid and Fissure Cream
- •Rite Aid Eye Drops Dry Eye Relief
- •Abreva Rapid Pain Relief
- •hemorrhoidal
- •GNP Hemorrhoidal Maximum Strength
- •La Roche Posay Laboratoire Dermatologique Cicaplast Defense B5 Skin Protectant
- •Genteal Tears
- •Exchange Select Maximum Redness Relief Eye Drops
- •Artificial Tears Lubricant Eye Drops
- •Glycerin Children
- •Proctozone-G
- •Refresh Relieva PF
- •Family Care Redness Relief
- •Walgreens Adult Glycerin Laxative
- •Walgreen Glycerin Adult
- •Walgreens Multi-Symptom Relief Eye Drops
- •Walgreens Eye Drops Maximum Redness Relief 15mL
- •Sore Throat
- •Hemorrhoidal Pain Relief Cream
- •GenTeal Tears (Moderate)
- •Anubis Barcelona Vital Line
- •Antibacterial Cooling Breeze
- •Eye Love Heyedrate Long Lasting Hydration
- •Tyson 2.0 Mike Red Eye Drops For Dry High Eyes
- •Droptics Dry Eye Relief
- •Glycerin Laxative
- •Signature Care Eye Drops Redness and Dry Eye Relief
- •hemorrhoidal maximum strength pain relief
- •TopCare Health Dry Eye Relief Eye Drops
- •Topcare Maximum Redness Relief Eye Drops
- •Sunmark Dry Eye Relief
- •GoodSense Redness Relief Plus
- •Family Wellness Maximum Redness Relief Eye Drops
- •Lemon Glycerine Swabsticks
- •Clear Eyes Cooling Redness Relief
- •Artificial Tears
- •Lemon
- •Family Wellness
- •La Roche Posay Laboratoire Dermatologique Cicaplast Defense B5
- •Pranicura 5
- •Equate Optimal Hydration Lubricant Eye Drops
- •Equate Lubricant Eye Drops
- •Miracle FootCream Lemon
- •Regener-Eyes LITE
- •St Moriz suncare body sunscreen spf30
- •Lacrifresh Hydrapf
- •Ripple
- •Antibacterial Delightful Sweetness
- •Antibacterial Dreamy Florals
- •Antibacterial BOLD Citrus
- •Antibacterial Fruity ZEST
- •Code Red Eye Drops Micro
- •Mens Massage Cream
- •Bunnies Bum Soothing Hemorrhoidal
- •Beautyturess Collagen Moisturizing Firming 14-Piece Set
- •Cold Sore Fast-Acting Pain Relief
- •7 Select Redness Relief
- •Burts Bees Rapid Rescue Cold Sore Treatment
- •Glycerinum
- •Oasis Tears Preservative-Free Lubricant Eye
- •Nikzon Hemorrhoidal
- •GoodSense Hemorrhoidal Pain Relief
- •Viva Hydration Boost
- •Discount Drug Mart Redness Relief Eye Drops
- •Medics Choice Fresh and Soothe
- •Glycerin Combination 9304
- •Clear Eyes Maximum Redness Relief
- •No More Products
- •Prevention Oncology Mouth Rinse
- •Doctor Butler Hemorrhoid and Fissure Advanced Formula
- •Buddate Inonotus Obliquus Water Brilliance MASK
- •Buddate Lotus Moisture Essence
- •AN12 Secret Therapy Feminine Cleanser
- •Anubis Barcelona Protective Line
- •Brain Liquescence
- •Sefudun Fungal NAIL Patches
- •Mens Massage Oil
- •Anal Care GLO pack
- •Atti amour Rose Anti-Aging Repair Moisturizing Cream
- •Moisture Oyster
- •Crocodile Tears Lubricant Eye Drops
- •Signature Care Hemorrhoidal Cream (with applicator)
- •Meijer Redness Relief
- •Xpect Industrial Eye Relief
- •Equate Eye Drops Dry Eye Relief
- •Glycerol-Saline Control
- •Refresh Optive Drops
- •Exchange Select Artificial Tears Lubricant Eye Drops
- •Medics Choice Eye Drops Maximum Redness Relief
- •Proctozone GMax
- •Cleareyes Redness Relief
- •Walgreens Glycerin
- •Harris Teeter Eye Drops Artificial Tears
- •Hydro Gel
- •Foster and Thrive Redness Relief Eye Drops
- •Bliss GVS
- •Recticare
- •Eyeganics Organic Tears
- •Rain Daily Hydration and Comfort For Dry Eyes
- •Lacrifresh Hydramaxpf
- •Hemorrhoidal Cream with Aloe
- •Salicylic acid foot gel
- •Hydro Boosting Eye Cream
- •ElixirLidoFast Rapid Relief
- •Antifungal cream
- •Up and Up Hemorrhoidal
- •Rite-Aid Childrens Glycerin Laxative
- •Hemorrhoidal Pain Relief with Aloe and VitaminE
- •Hemorrhoidal Pain Relief
- •Kroger Eye Drops Redness Relief
- •topcare hemorrhoidal
- •HEB Dry Eye Eye Drops
- •Equaline Hemorrhoidal
- •Meijer Maximum Redness Relief and Lubricant
- •GNP Eye Drops Dry Eye Relief
- •GNP Eye Drops Redness and Dry Eye Relief
- •DG Maximum Strength Redness Relief
- •Core Values Eye Drops Dry Eye Relief
- •Winco Maximum Redness Relief Eye Drops
- •Clear Eyes Redness Relief Handy Pocket Pal
- •Walgreens Redness Relief Eye Drops 15mL
- •Harris Teeter Redness Relief Eye Drops
- •CVS Health Hemorrhoidal Cream
- •Bliss GVS Children
- •Zenibell Snail Intensive Toner
- •Thera Plus Hemorrhoidal
- •Bestmade Natural Products BM164
- •Melao HAIR Growth Mousse
- •Bloop Hemorrhoid Relief Topical
- •Hemorrhoid, Fissure, ProctalgiaSuppositories
- •Hemorrhoid, Fissure, Proctalgia Relief Wash
- •SilkTears
- •Tucks Triple Relief Hemorrhoidal
- •Good Sense Hemorrhoidal Maximum Strength Pain Relief
- •blink boost
- •Kroger Hemorrhoid
- •Fleet
- •Meijer Dry Eye Relief
- •CVS Maximum OTC Strength Hemorrhoidal with Aloe
- •Hemorrhoidal WITH Lidocaine
- •CVS Maximum Redness Relief
- •Refresh Optive Mega-3 PF
- •Clear Eyes Nighttime
- •Chloraseptic Sore Throat Max
- •Lemon Glycerin
- •Aveeno Skin Relief Healing
- •Homeoplex D
- •Zenibell Snail IntensiveCream
- •aewajin Derma Hydrocell
- •Topwin Speedy Enema
- •Equate Redness and Dry Eye Relief
- •Virility Liquescence
- •Diaper cream
- •Hydrasphere PLUS
- •Advanced Eye Relief Dry Eye Rejuvenation
- •Oasis Tears Plus Preservative-Free Lubricant Eye
- •GNP EyeDrops Maximum Redness Relief
- •Colirio Oftal-Mycin
- •equate hemorrhoidal
- •Redness and Dry Eye Relief
- •Refresh Digital
- •Finafta
- •Stratuscare Adult Glycerin
- •Dry Eye Relief Sterile Lubricant Eye Drops
- •Walgreens Hemorrhoidal Pain Relief
- •Harris Teeter Eye Drops Maximum Redness Relief
- •Foaming Facial Cleanser
- •Equate Redness and Dry Eye Relief Eye Drops
- •Caring Mill Lubricant Eye Drops
- •Up and Up Hemorrhoid MAX Strength
- •Anubis Barcelona Spa Line
- •Anubis Barcelona Total Hydrating
- •Equaline Redness Relief Lubricant Eye Drops
- •Skin Cleaning Care Wipes
- •Hemorrhoid, Fissure, Proctalgia Ointments
- •Atti amour Rose Anti-Aging Repair Classic Essence
- •Atti amour Rose Anti-Aging Repair Serum
- •Dermatool Hemorrhoidal
- •Hemorrhoid and Fissure
- •Norms Hemorrhoid
- •Soothe
- •Blink Nourish Dry Eye
- •Oasis Tears PF PLUS Preservative-Free Lubricant Eye
- •Artifical Tears
- •Family Wellness Hemorrhoid
- •Refresh Relieva
- •Refresh Relieva Preservative Free
- •Refresh Digital PF
- •B05 Gluco Balance
- •Clear Eyes Sensitive
- •Upside Down Pain Relief
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No Shortage
Industrial Uses
Used in 21 sectors as 17 functional roles.
- •Humectant in All Other Chemical Product and Preparation Manufacturing (100%)Processing—repackaging
- •Diluent in All Other Basic Inorganic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Monomers in Printing and Related Support ActivitiesProcessing—repackaging
- •Monomers in Printing Ink ManufacturingProcessing—repackaging
- •Humectant in Wholesale and Retail TradeProcessing—incorporation into formulation, mixture, or reaction product
- •Lubricating agent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in All Other Basic Organic Chemical Manufacturing (46%)Processing—incorporation into formulation, mixture, or reaction product
- •Surfactant (surface active agent) in All Other Basic Organic Chemical Manufacturing (43%)Processing—incorporation into formulation, mixture, or reaction product
- •Flavoring and nutrient in Agriculture, Forestry, Fishing and Hunting (11%)Processing—incorporation into formulation, mixture, or reaction product
- •Surfactant (surface active agent) in Miscellaneous Manufacturing (30%)Processing—incorporation into formulation, mixture, or reaction product
- •Surfactant (surface active agent) in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (70%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Surfactant (surface active agent) in Food, beverage, and tobacco product manufacturing (100%)Use—non-incorporative activities
- •Fuel agents in Petrochemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Tanning agents not otherwise specified in Textiles, apparel, and leather manufacturing (100%)Processing—incorporation into article
- •Lubricating agent in All Other Chemical Product and Preparation Manufacturing (100%)Processing as a reactant
- •Surfactant (surface active agent) in Oil and Gas Drilling, Extraction, and Support activities (10%)Processing—incorporation into formulation, mixture, or reaction product
- •Surfactant (surface active agent) in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Humectant in Paper Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in All Other Basic Organic Chemical ManufacturingProcessing—repackaging
- •Lubricating agent in Rubber Product Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Solubility enhancer in Textiles, apparel, and leather manufacturing (100%)Processing—incorporation into article
- •Emulsifier in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Plastics Material and Resin Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Humectant in Printing and Related Support ActivitiesUse—non-incorporative activities
- •Intermediate in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Lubricating agent in Pharmaceutical and Medicine Manufacturing (30%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in Food, beverage, and tobacco product manufacturing (55%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in All Other Chemical Product and Preparation Manufacturing (25%)Processing—incorporation into formulation, mixture, or reaction product
- •Tanning agents not otherwise specified in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Monomers in ConstructionProcessing as a reactant
- •Solvent in Paint and Coating ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Abrasives in Pesticide, Fertilizer, and Other Agricultural Chemical ManufacturingUse—non-incorporative activities
- •Flow promoter in Printing Ink ManufacturingProcessing—repackaging
- •Anti-freeze agent in Pesticide, Fertilizer, and Other Agricultural Chemical ManufacturingUse—non-incorporative activities
- •Dust suppressant in Pesticide, Fertilizer, and Other Agricultural Chemical ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Anti-slip agent in Machinery ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
Vendor Pricing
$0.01/gAngene Chemical
CountryChina (registered: Hong Kong)
Pack$125.00 / 25 kg
Purity98%
Vendors23 available
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
22 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| A2B Chem LLC | United States | $0.01 | 20 kg | 98% |
| AA BLOCKS | United States | $0.01 | 20 kg | 99% |
| Fluorochem UK | United Kingdom | $0.01 | 5 kg | 99% |
| Sigma-Aldrich (Rush Stock) | Germany | $0.02 | 25 kg | — |
| Sigma-Aldrich | Germany | $0.02 | 25 kg | — |
| BLD Pharmatech Co., Limited | United States | $0.03 | 1 kg | 99.5% |
| BLD Pharmatech GmbH | Germany | $0.03 | 1 kg | 99.5% |
| BLD Pharmatech Ltd. | China | $0.03 | 1 kg | 99.5% |
| Ambeed, Inc. | United States | $0.03 | 1 kg | 99.5% |
| Fluorochem EU | Germany | $0.03 | 1 kg | 99% |
| Chemscene | United States | $0.05 | 1 kg | — |
| AK Scientific Specialized | United States | $0.06 | 1 kg | 98% |
| AK Scientific, Inc. | United States | $0.08 | 1 kg | 99.5% |
| AstaTech, Inc | United States | $0.19 | 500 g | 95% |
| Angene International Limited | United States | $0.22 | 500 g | 99% |
| Combi-Blocks, Inc. | United States | $0.25 | 1 kg | 98% |
| TargetMol Chemicals | China → United States | $50.00 | 1 g | — |
| MedChemExpress MCE | Sweden | $336.38 | 500 mg | — |
| Labotest KG | Germany | $453.00 | 1000 mg | 90% |
| Otava, Ltd. | Ukraine | $2280.00 | 50 mg | 95% |
| Otava, Ltd. (2 weeks) | Ukraine | $2724.00 | 50 mg | 90% |
| Angene | China → Hong Kong | $4266.67 | 30 mg | 98% |
Chemical Identity
CAS56-81-5
PubChem CID753
DTXSIDDTXSID9020663
FormulaC3H8O3
Mol. Weight92.09 g/mol
SMILESC(C(CO)O)O
Data Sources
- EPA CompTox (DSSTox) · DTXSID9020663Retrieved 2026-04-06
- PubChem · compound 753Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- FDA Drug ShortagesRetrieved 2026-06-13
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Glycerol (CAS 56-81-5) https://chemicalindependence.com/chemical/56-81-5/ EPA CompTox (DSSTox): DTXSID9020663. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020663 PubChem: 753. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/753 EPA Chemical Data Reporting: 56-81-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA Drug Shortages: CAS 56-81-5. Retrieved 2026-06-13. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 152000,290545 for CAS 56-81-5. Reporting year: 2024. https://usatrade.census.gov/