Glycine
Drug ingredientCAS 56-40-6
This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$503M
Top sourceChina 25%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 292249 · basket
EPA reports by year
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
These shares come from HS customs code 292249, which covers 170 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
Source Countries
Country of origin for US imports, from Census customs data (2024).
CN 25%ChinaIN 17%IndiaSG 13%SingaporeIT 9%ItalyCH 7%Switzerland
- Argentina
- Poland
- Portugal
- Lithuania
- Ukraine
- Finland
- Spain
- Egypt
- Sweden
- Austria
- Israel
- Latvia
- Belgium
- Ireland
- Mexico
- Australia
- Peru
- Czech Republic
- Colombia
- Hong Kong
EPA-registered manufacturers (2)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Geo Specialty Chemicals
Macdermid
Domestic parents -- activity not disclosed (3)
EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.
Chemical Distribution Network
Emd Holding
Silver Fern Chemical
EPA-registered importers (6)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Syensqo Sa · BE Belgium
Entegris
Resonac America
Solvay
Soyventis North America
Show all 6
Wilbur-Ellis Holdings Ii
19 FDA-registered drug labelers
Ajinomoto Co., Inc.
Ajinomoto Health & Nutrition North America Inc.
B. Braun Medical Inc.
Baxter Healthcare Company
Baxter Healthcare Corporation
Chattem Chemicals, Inc.
DNA Labs, Inc.
Evonik Rexim (Nanning) Pharmaceutical Co., Ltd.
Fresenius Kabi USA, LLC
GEO Specialty Chemicals Inc.
ICU Medical Inc.
Nutritional Specialties, Inc.
ProBlen
Professional Compounding Centers of America
Qingdao Biopeptek Co., Ltd.
Spectrum Laboratory Products, Inc.
Willow Birch Pharma, LLC
Yuki Gosei Kogyo Co., Ltd.
Zen Chemicals Private Limited
Why It Matters
Sectors
HealthAgricultureFoodWaterMetals & MiningCore Chemicals
Downstream Uses
Appears in 16 drug and cosmetic product listings (FDA).
- •Aminosyn-PF
- •Plenamine
- •Kabiven
- •Clinimix
- •Clinimix E
- •Glycine
- •Clinisol
- •ProSol
Show all 16
- •TrophAmine
- •Aminosyn II
- •N-16
- •Travasol
- •Perikabiven
- •Metab
- •HGH Complex
- •Premasol - sulfite-free (Amino Acid)
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
Used in 8 sectors as 12 functional roles.
- •Chelating agent in Agriculture, Forestry, Fishing and Hunting (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Flavoring and nutrient in Food, beverage, and tobacco product manufacturing (36%)Processing—incorporation into formulation, mixture, or reaction product
- •Chelating agent in Pharmaceutical and Medicine Manufacturing (3%)Processing—incorporation into formulation, mixture, or reaction product
- •Flavoring and nutrient in Agriculture, Forestry, Fishing and Hunting (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Flavoring and nutrient in Pharmaceutical and Medicine Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
- •pH regulating agent in All Other Chemical Product and Preparation Manufacturing (12%)Processing—incorporation into formulation, mixture, or reaction product
- •pH regulating agent in Pharmaceutical and Medicine Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Abrasives in Miscellaneous ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Soil amendments (fertilizers) in Pesticide, Fertilizer, and Other Agricultural Chemical ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Abrasives in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Plating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Chelating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Etching agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Intermediate in All Other Basic Organic Chemical Manufacturing (100%)Processing as a reactant
- •Flocculating agent in Utilities (100%)Processing—repackaging
- •Lubricating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Binder in Food, beverage, and tobacco product manufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Flame retardant in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
Vendor Pricing
$0.02/gAA BLOCKS
CountryUnited States
Pack$11.00 / 500 g
Purity98%
Vendors32 available
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
31 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| A2B Chem LLC | United States | $0.02 | 500 g | 98% |
| BLD Pharmatech GmbH | Germany | $0.03 | 1 kg | 99% |
| BLD Pharmatech Ltd. | China | $0.03 | 1 kg | 99% |
| Apollo Scientific UK | United Kingdom | $0.03 | 5 kg | 99% |
| Sigma-Aldrich (Rush Stock) | Germany | $0.03 | 25 kg | 99% |
| Sigma-Aldrich | Germany | $0.03 | 25 kg | 99% |
| Fluorochem EU | Germany | $0.04 | 1 kg | 98% |
| Fluorochem UK | United Kingdom | $0.04 | 1 kg | 98% |
| Acrotein ChemBio, Inc. | United States | $0.04 | 1 kg | — |
| Chemscene | United States | $0.05 | 1 kg | — |
| AK Scientific, Inc. | United States | $0.07 | 1 kg | 99% |
| Apollo Scientific US | United Kingdom | $0.15 | 1 kg | — |
| AstaTech, Inc | United States | $0.23 | 100 g | 95% |
| Combi-Blocks, Inc. | United States | $0.25 | 1 kg | 99% |
| Biopharma PEG Scientific Inc. | United States | $0.30 | 500 g | 99% |
| MedChemExpress MCE | Sweden | $11.52 | 25 g | 99.93% |
| CliniSciences GmbH | Switzerland | $32.25 | 1 g | 99% |
| Molnova | China | $43.00 | 1 g | 99% |
| TargetMol Chemicals | China → United States | $48.00 | 1 g | 99.54% |
| Labotest KG | Germany | $217.80 | 5000 mg | 90% |
| Specs | Netherlands | $376.31 | 1 g | 90% |
| Otava, Ltd. | Ukraine | $460.00 | 250 mg | 95% |
| ChemFaces | China | $1500.00 | 20 mg | 98% |
| Vitas M Chemical Limited | Hong Kong | $3170.00 | 100 mg | 90% |
| Princeton BioMolecular Research (SC) | United States | $4200.00 | 50 mg | 90% |
| Asinex | Netherlands | $6461.40 | 100 mg | 90% |
| Key Organics Ltd. | United Kingdom | $6900.00 | 10 mg | 90% |
| AA BLOCKS (2 weeks) | United States | $8260.00 | 100 mg | — |
| A2B Chem LLC (2 weeks) | United States | $14540.00 | 100 mg | — |
| Aaron Chemicals LLC | Hong Kong | $17410.00 | 100 mg | — |
| TimTec, LLC (back-ordered) | United States | $32000.00 | 15 mg | 94% |
Chemical Identity
CAS56-40-6
PubChem CID750
DTXSIDDTXSID9020667
FormulaC2H5NO2
Mol. Weight75.07 g/mol
SMILESC(C(=O)O)N
Data Sources
- EPA CompTox (DSSTox) · DTXSID9020667Retrieved 2026-04-06
- PubChem · compound 750Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- FDA National Drug Code directoryRetrieved 2026-04-07
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Glycine (CAS 56-40-6) https://chemicalindependence.com/chemical/56-40-6/ EPA CompTox (DSSTox): DTXSID9020667. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020667 PubChem: 750. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/750 EPA Chemical Data Reporting: 56-40-6. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 56-40-6. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292249 for CAS 56-40-6. Reporting year: 2024. https://usatrade.census.gov/