Cantharidin

Drug ingredient

CAS 56-25-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$64M

Top sourceChina 37%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293219 · basket

These shares come from HS customs code 293219, which covers 136 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 37%ChinaIT 23%ItalyJP 20%JapanIN 12%IndiaES 2%Spain

Belgium
Germany
Netherlands
Canada
Mexico
Slovakia
Malaysia
Portugal
Taiwan
Sweden
Latvia
Israel

8 FDA-registered drug labelers

Curia New York, Inc.

DARMERICA, LLC

LETCO MEDICAL, LLC

PEL HEALTHCARE LLC

Professional Compounding Centers of America

Verrica Pharmaceuticals Inc.

Wavelength Enterprises Ltd.

Wuxi Fortune Pharmaceutical Co., Ltd

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Ycanth

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS56-25-7

PubChem CID5944

DTXSIDDTXSID7041752

FormulaC10H12O4

Mol. Weight196.2 g/mol

SMILESCC12C3CCC(C1(C(=O)OC2=O)C)O3

Data Sources

PubChem · compound 5944Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Cantharidin (CAS 56-25-7) https://chemicalindependence.com/chemical/56-25-7/ PubChem: 5944. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5944 EPA TSCA Inventory: CAS 56-25-7. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293219 for CAS 56-25-7. Reporting year: 2024. https://usatrade.census.gov/