Norspermidine

CAS 56-18-8

EPA’s 2023 records show zero U.S. production of this chemical.

US productionZero

Import value, 2024$119M

Import volumeCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Top sourceJapan 33%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292129 · basket

EPA reports by year

2023: US production Zero · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 292129, which covers 69 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

JP 33%JapanCA 14%CanadaNL 10%NetherlandsSE 7%SwedenDE 7%Germany

United Arab Emirates
Czech Republic
Mexico
Malaysia
South Korea
Turkey
Norway
Australia
Ukraine
Russia
Spain
Latvia

EPA-registered importers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Basf Se · DE Germany

Basf

Why It Matters

Sectors

Core Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in All Other Basic Organic Chemical ManufacturingProcessing as a reactant

Vendor Pricing

$0.17/gSigma-Aldrich (Rush Stock)

CountryGermany

Pack$85.10 / 500 g

Purity98%

Vendors9 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

8 more vendors

Vendor	Country	$/g	Pack	Purity
Sigma-Aldrich	Germany	$0.17	500 g	98%
AK Scientific Specialized	United States	$0.52	100 g	95%
AK Scientific, Inc.	United States	$0.55	500 g	99%
MedKoo Biosciences, Inc	United States	$0.83	500 g	98%
A2B Chem LLC	United States	$1.20	100 g	98%
Combi-Blocks, Inc.	United States	$1.20	100 g	98%
AA BLOCKS	United States	$1.36	25 g	99%
Labotest KG	Germany	$217.80	5000 mg	90%

Chemical Identity

CAS56-18-8

PubChem CID5942

DTXSIDDTXSID0025440

FormulaC6H17N3

Mol. Weight131.22 g/mol

SMILESC(CN)CNCCCN

Data Sources

EPA CompTox (DSSTox) · DTXSID0025440Retrieved 2026-04-06
PubChem · compound 5942Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Norspermidine (CAS 56-18-8) https://chemicalindependence.com/chemical/56-18-8/ EPA CompTox (DSSTox): DTXSID0025440. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID0025440 PubChem: 5942. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/5942 EPA Chemical Data Reporting: 56-18-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 56-18-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292129 for CAS 56-18-8. Reporting year: 2024. https://usatrade.census.gov/