Tetrakis(hydroxymethyl)phosphonium sulfate

CAS 55566-30-8

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$598M

Top sourceChina 89%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293149 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 293149, which covers 114 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 89%ChinaIN 4%IndiaCA 3%CanadaDE 2%GermanyAR 1%Argentina

United Kingdom
Italy
Mexico
Japan
Switzerland
Hong Kong
Ukraine
Finland
Sweden
Spain
Poland
Slovakia
Netherlands
Singapore
Taiwan
South Korea
Czech Republic

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Tri-Chem Industries

Domestic parents -- activity not disclosed (5)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Clariant

Coastal Chemical

Harcros Chemicals

Solvay

Wilbur-Ellis Holdings Ii

EPA-registered importers (7)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Syensqo Sa · BE Belgium

Access Chemicals & Services

Brenntag

Chemical Distribution Network

Special Materials

Show all 7

Valudor Products

Wego Chemical Group

Why It Matters

Sectors

EnergyTextilesConsumer ProductsCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 2 sectors as 3 functional roles.

•Processing aids, specific to petroleum production in Oil and Gas Drilling, Extraction, and Support activities (0%)Use—non-incorporative activities
•Flame retardant in Textiles, apparel, and leather manufacturingProcessing as a reactant
•Chelating agent in Oil and Gas Drilling, Extraction, and Support activities (100%)Processing—incorporation into formulation, mixture, or reaction product

Chemical Identity

CAS55566-30-8

PubChem CID41478

DTXSIDDTXSID0021331

FormulaC8H24O12P2S

Mol. Weight406.28 g/mol

SMILESC(O)[P+](CO)(CO)CO.C(O)[P+](CO)(CO)CO.[O-]S(=O)(=O)[O-]

Data Sources

EPA CompTox (DSSTox) · DTXSID0021331Retrieved 2026-04-06
PubChem · compound 41478Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Tetrakis(hydroxymethyl)phosphonium sulfate (CAS 55566-30-8) https://chemicalindependence.com/chemical/55566-30-8/ EPA CompTox (DSSTox): DTXSID0021331. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID0021331 PubChem: 41478. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/41478 EPA Chemical Data Reporting: 55566-30-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 55566-30-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293149 for CAS 55566-30-8. Reporting year: 2024. https://usatrade.census.gov/