Trimethobenzamide hydrochloride

Drug ingredient

CAS 554-92-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 554-92-7
1 HCl
US productionNot reported
Import value, 2024$872M
Top sourceSwitzerland 44%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292429 · basket

These shares come from HS customs code 292429, which covers 203 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CH 44%SwitzerlandCN 19%ChinaIN 12%IndiaJP 9%JapanIE 6%Ireland
9 FDA-registered drug labelers
Bryant Ranch Prepack
Chartwell RX, LLC
Emcure Pharmaceuticals Limited
Henry Schein, Inc
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.
HF Acquisition Co LLC, DBA HealthFirst
Lupin Pharmaceuticals,Inc.
Par Health USA, LLC
Siegfried AG

Why It Matters

Sectors
Health
Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

  • •Tigan(R) (Trimethobenzamide Hydrochloride)
  • •Trimethobenzamide Hydrochloride
  • •Tigan
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$9.40/gAaron Chemicals LLC
CountryHong Kong
Pack$47.00 / 5 g
Purity98%
Vendors19 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS554-92-7
PubChem CID68385
DTXSIDDTXSID7047774
FormulaC21H29ClN2O5
Mol. Weight424.9 g/mol
SMILESCN(C)CCOC1=CC=C(C=C1)CNC(=O)C2=CC(=C(C(=C2)OC)OC)OC.Cl

Data Sources

Brief citations

Trimethobenzamide hydrochloride (CAS 554-92-7) https://chemicalindependence.com/chemical/554-92-7/ PubChem: 68385. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/68385 FDA National Drug Code directory: CAS 554-92-7. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292429 for CAS 554-92-7. Reporting year: 2024. https://usatrade.census.gov/