Methazolamide

Drug ingredient

CAS 554-57-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$2.0B

Top sourceIreland 63%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293590 · basket

These shares come from HS customs code 293590, which covers 182 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 63%IrelandSG 14%SingaporeIN 7%IndiaCN 7%ChinaCH 2%Switzerland

Portugal
Spain
Italy
Austria
Israel
Hungary
Canada
South Korea
Netherlands
Finland
Poland
Indonesia
Ukraine
Mexico
South Africa
Croatia
Greece
Taiwan
Hong Kong

15 FDA-registered drug labelers

Ajanta Pharma USA Inc.

ANI Pharmaceuticals, Inc.

AX Pharmaceutical Corp

Azico Biophore India Private Limited

Bausch & Lomb Incorporated

Bryant Ranch Prepack

DARMERICA, LLC

DELMAR CHEMICALS INC

Fine Chemicals Corporation (PTY) Ltd.

Golden State Medical Supply, Inc.

Micro Labs Limited

NorthStar Rx LLC

Padagis US LLC

Precision Dose, Inc.

Willow Birch Pharma, Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Methazolamide

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$38.00/gMedKoo Biosciences, Inc

CountryUnited States

Pack$950.00 / 25 g

Purity98%

Vendors4 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

3 more vendors

Vendor	Country	$/g	Pack	Purity
Molnova	China	$86.00	1 g	99%
AA BLOCKS	United States	$318.60	5 g	98%
Apexbio Technology LLC	United States	$1020.00	50 mg	99.79%

Chemical Identity

CAS554-57-4

PubChem CID4100

DTXSIDDTXSID1023281

FormulaC5H8N4O3S2

Mol. Weight236.3 g/mol

SMILESCC(=O)N=C1N(N=C(S1)S(=O)(=O)N)C

Data Sources

PubChem · compound 4100Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Methazolamide (CAS 554-57-4) https://chemicalindependence.com/chemical/554-57-4/ PubChem: 4100. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/4100 FDA National Drug Code directory: CAS 554-57-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293590 for CAS 554-57-4. Reporting year: 2024. https://usatrade.census.gov/