Amitriptyline hydrochloride
Drug ingredientCAS 549-18-8
This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.
EPA lists this chemical as inactive, meaning no company reported making, importing or processing it in the US from 2006 to 2016.
Why supply is unknownProduction is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 292149 · basket
These shares come from HS customs code 292149, which covers 80 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
- Israel
- Ireland
- Czech Republic
- Singapore
- Slovakia
- Lithuania
- Belgium
- Australia
48 FDA-registered drug labelers
Why It Matters
Appears in 4 drug and cosmetic product listings (FDA).
- •Amitriptyline Hydrochloride
- •Chlordiazepoxide and Amitriptyline Hydrochloride
- •Amitriptyline HCL
- •Perphenazine and Amitriptyline Hydrochloride
Vendor Pricing
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
26 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| A2B Chem LLC | United States | $1.02 | 500 g | 97% |
| AA BLOCKS | United States | $1.08 | 500 g | 97% |
| Sigma-Aldrich (Rush Stock) | Germany | $2.31 | 250 g | 98% |
| Sigma-Aldrich | Germany | $2.31 | 250 g | 98% |
| Aaron Chemicals LLC | Hong Kong | $2.95 | 100 g | 98% |
| Angene Chemical | China → Hong Kong | $2.98 | 100 g | 98% |
| AstaTech (2 weeks) | United States | $4.08 | 25 g | 95% |
| AK Scientific, Inc. | United States | $4.68 | 25 g | 98% |
| Cayman Europe | Estonia | $5.90 | 25 g | 98% |
| Fluorochem UK | United Kingdom | $6.18 | 25 g | 95% |
| Angene International Limited | United States | $8.60 | 25 g | 98% |
| MedChemExpress MCE | Sweden | $8.71 | 5 g | 99.94% |
| Apexbio Technology LLC | United States | $14.80 | 5 g | 99.95% |
| MedKoo Biosciences, Inc | United States | $26.00 | 25 g | 98% |
| CliniSciences GmbH | Switzerland | $45.15 | 1 g | 98% |
| Molnova | China | $48.00 | 1 g | 99% |
| AK Scientific Specialized | United States | $197.00 | 1 g | 99% |
| Interbioscreen | Hong Kong | $354.00 | 10 g | 95% |
| A2B Chem LLC (1 week) | United States | $3450.00 | 100 mg | 98% |
| AA BLOCKS (1 week) | United States | $3800.00 | 100 mg | 98% |
| Vitas M Chemical Limited | Hong Kong | $4020.00 | 50 mg | 90% |
| Princeton BioMolecular Research (SC) | United States | $4200.00 | 50 mg | 90% |
| Angene | China → Hong Kong | $4266.67 | 30 mg | 98% |
| Key Organics Ltd. | United Kingdom | $6900.00 | 10 mg | 97% |
| ChemDiv, Inc. | United States | $14800.00 | 5 mg | 90% |
| TimTec, LLC (back-ordered) | United States | $32000.00 | 15 mg | 94% |
Chemical Identity
Data Sources
- PubChem · compound 11065Retrieved 2026-04-07
- EPA TSCA InventoryRetrieved 2026-04-24
- FDA National Drug Code directoryRetrieved 2026-04-07
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Amitriptyline hydrochloride (CAS 549-18-8) https://chemicalindependence.com/chemical/549-18-8/ PubChem: 11065. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/11065 EPA TSCA Inventory: CAS 549-18-8. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292149 for CAS 549-18-8. Reporting year: 2024. https://usatrade.census.gov/