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Nicardipine hydrochloride

Drug ingredient

CAS 54527-84-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 54527-84-3
1 HCl
US productionNot reported
Import value, 2024$1.3B
Top sourceChina 32%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293339 · basket

These shares come from HS customs code 293339, which covers 397 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 32%ChinaIN 15%IndiaDE 10%GermanyBE 9%BelgiumCH 8%Switzerland
35 FDA-registered drug labelers
American Regent, Inc.
Amici Pharma Inc
Amneal Pharmaceuticals NY LLC
ANI Pharmaceuticals, Inc.
Apothecon Pharmaceuticals Pvt Ltd
Archis Pharma LLC
Armas Pharmaceuticals Inc.
Baxter Healthcare Corporation
Bionpharma Inc.
Burel Pharmaceuticals, LLC
Caplin Steriles Limited
Chengdu Shuode Pharmaceutical Co., Ltd
Cipla USA Inc.
Civica, Inc.
Epic Pharma, LLC
Eugia US LLC
Fresenius Kabi USA, LLC
Glenmark Pharmaceuticals Inc., USA
HF Acquisition Co LLC, DBA HealthFirst
Hikma Pharmaceuticals USA Inc.
Lifestar Pharma LLC
Lusochimica SPA
Meitheal Pharmaceuticals Inc.
Metrochem API Private Limited
Micro Labs Limited
MSN Laboratories Private Limited
Olon SpA
PuraCap Laboratories LLC dba Blu Pharmaceuticals
Qilu Pharmaceutical Co., Ltd.
Sagent Pharmaceuticals
Sichuan Qingmu Pharmaceutical Co., Ltd.
Somerset Therapeutics, LLC
West-Ward Pharmaceuticals Corp
WG Critical Care, LLC
Zydus Pharmaceuticals USA Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

  • •Nicardipine Hydrochloride
  • •Cardene IV
  • •Nicardipine Hydrochloride in Sodium Chloride
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$1.56/gCombi-Blocks, Inc.
CountryUnited States
Pack$780.00 / 500 g
Purity98%
Vendors21 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

20 more vendors
VendorCountry$/gPackPurity
A2B Chem LLCUnited States$1.66500 g99%
AA BLOCKSUnited States$1.75500 g99%
AK Scientific SpecializedUnited States$1.86100 g95%
Ambeed, Inc.United States$2.4025 g99%
AK Scientific, Inc.United States$2.49100 g98%
Angene International LimitedUnited States$6.6425 g99%
Aaron Chemicals LLCHong Kong$8.9625 g98%
Angene ChemicalChina → Hong Kong$9.0825 g98%
AstaTech, IncUnited States$13.3225 g95%
Cayman EuropeEstonia$24.0425 g98%
Apexbio Technology LLCUnited States$38.005 g99.85%
MolnovaChina$43.001 g99%
TargetMol ChemicalsChina → United States$48.001 g99.99%
MedChemExpress MCESweden$60.025 g99.73%
Sigma-Aldrich (Rush Stock)Germany$94.9910 g98%
Sigma-AldrichGermany$94.9910 g98%
MedKoo Biosciences, IncUnited States$95.0010 g98%
CliniSciences GmbHSwitzerland$322.50100 mg99%
AngeneChina → Hong Kong$4266.6730 mg98%
Key Organics Ltd.United Kingdom$6900.0010 mg97%

Chemical Identity

CAS54527-84-3
PubChem CID41114
DTXSIDDTXSID9046992
FormulaC26H30ClN3O6
Mol. Weight516 g/mol
SMILESCC1=C(C(C(=C(N1)C)C(=O)OCCN(C)CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC.Cl

Data Sources

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Brief citations

Nicardipine hydrochloride (CAS 54527-84-3) https://chemicalindependence.com/chemical/54527-84-3/ PubChem: 41114. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/41114 FDA National Drug Code directory: CAS 54527-84-3. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293339 for CAS 54527-84-3. Reporting year: 2024. https://usatrade.census.gov/