Propafenone

Drug ingredient

CAS 54063-53-5

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$197M

Top sourceChina 36%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292219 · basket

These shares come from HS customs code 292219, which covers 167 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 36%ChinaIT 15%ItalyDE 14%GermanyIN 7%IndiaHU 5%Hungary

Saudi Arabia
Lithuania
Canada
Ukraine
Israel
Singapore
Mexico
Ireland
Netherlands
Malaysia
Slovakia
Denmark
Finland
Latvia
Greece
Austria

1 FDA-registered drug labeler

PharmaZell GmbH

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No Shortage

Shortage History

Rows group FDA shortage filings by drug product. Each manufacturer makes its own FDA shortage filing, so one product can carry several reports at once: Available, Limited Availability, Unavailable or to be discontinued.

to be discontinued
Propafenone Hydrochloride Capsule, Extended Release
Shortage listed since May 14, 2025

See all current drug shortages

Vendor Pricing

$43.60/gAaron Chemicals LLC

CountryHong Kong

Pack$218.00 / 5 g

Purity98%

Vendors18 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

17 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$50.20	5 g	98%
Combi-Blocks, Inc.	United States	$53.00	5 g	98%
BLD Pharmatech Ltd.	China	$54.80	5 g	99%
Ambeed, Inc.	United States	$60.20	5 g	99%
A2B Chem LLC	United States	$63.00	1 g	99%
AA BLOCKS	United States	$70.00	1 g	99%
BLD Pharmatech GmbH	Germany	$80.00	1 g	99%
BLD Pharmatech Co., Limited	United States	$140.00	250 mg	99%
AstaTech (2 weeks)	United States	$316.00	1 g	95%
TargetMol Chemicals	China → United States	$524.00	500 mg	99.69%
TargetMol Chemicals US	United States	$775.00	200 mg	99.69%
Molnova	China	$905.00	200 mg	99%
TargetMol Chemicals EU	Austria	$1050.00	100 mg	99.69%
MedChemExpress MCE	Sweden	$1621.40	100 mg	99.64%
Angene International Limited	United States	$2850.00	100 mg	98%
Vitas M Chemical Limited	Hong Kong	$4020.00	50 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	98%

Chemical Identity

CAS54063-53-5

PubChem CID4932

DTXSIDDTXSID9045184

FormulaC21H27NO3

Mol. Weight341.4 g/mol

SMILESCCCNCC(COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2)O

Data Sources

PubChem · compound 4932Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA Drug ShortagesRetrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Propafenone (CAS 54063-53-5) https://chemicalindependence.com/chemical/54063-53-5/ PubChem: 4932. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/4932 FDA National Drug Code directory: CAS 54063-53-5. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 54063-53-5. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 292219 for CAS 54063-53-5. Reporting year: 2024. https://usatrade.census.gov/