Isobutyl propionate

CAS 540-42-1

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$30M

Top sourceCanada 27%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291550 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 291550, which covers 61 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CA 27%CanadaCN 14%ChinaIT 13%ItalyMX 11%MexicoIN 10%India

Slovakia
Sweden
Argentina
Switzerland

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Eastman Chemical

Why It Matters

Sectors

Core Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in All Other Basic Organic Chemical ManufacturingProcessing as a reactant

Vendor Pricing

$0.11/gSigma-Aldrich (Rush Stock)

CountryGermany

Pack$454.29 / 4 kg

Purity98%

Vendors4 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

3 more vendors

Vendor	Country	$/g	Pack	Purity
Sigma-Aldrich	Germany	$0.11	4 kg	98%
Combi-Blocks, Inc.	United States	$0.48	500 g	98%
Labotest KG	Germany	$217.80	5000 mg	90%

Chemical Identity

CAS540-42-1

PubChem CID10895

DTXSIDDTXSID8060240

FormulaC7H14O2

Mol. Weight130.18 g/mol

SMILESCCC(=O)OCC(C)C

Data Sources

EPA CompTox (DSSTox) · DTXSID8060240Retrieved 2026-04-06
PubChem · compound 10895Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

← Back to Dashboard ← Back to Core Chemicals

Brief citations

Isobutyl propionate (CAS 540-42-1) https://chemicalindependence.com/chemical/540-42-1/ EPA CompTox (DSSTox): DTXSID8060240. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID8060240 PubChem: 10895. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/10895 EPA Chemical Data Reporting: 540-42-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 540-42-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 291550 for CAS 540-42-1. Reporting year: 2024. https://usatrade.census.gov/