Isoniazid

Drug ingredient

CAS 54-85-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 54-85-3
US productionNot reported
Import value, 2024$1.3B
Top sourceChina 32%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293339 · basket

These shares come from HS customs code 293339, which covers 397 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 32%ChinaIN 15%IndiaDE 10%GermanyBE 9%BelgiumCH 8%Switzerland
23 FDA-registered drug labelers
A-S Medication Solutions
American Health Packaging
ANUH PHARMA LIMITED
Aphena Pharma Solutions - Tennessee, LLC
Bryant Ranch Prepack
Calyx Chemicals & Pharmaceuticals Limited
Chartwell RX, LLC
CHONGQING HUAPONT SHENGCHEM PHARM. CO., LTD.
CMP Pharma, Inc.
Coupler LLC
DARMERICA, LLC
Genus Lifesciences
Marlex Pharmaceuticals, Inc.
Mylan Institutional Inc.
OMNIVIUM PHARMACEUTICALS LLC.
Preferred Pharmaceuticals, Inc.
Proficient Rx LP
REMEDYREPACK INC.
Sandoz Inc
Second Pharma Co., Ltd.
Teva Pharmaceuticals USA, Inc.
Topchem Pharmaceuticals Ltd
Yuki Gosei Kogyo Co., Ltd.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •isoniazid
FDA Shortage Status
No Shortage
Shortage History
  • to be discontinued

    Isoniazid Tablet

    Shortage listed since July 1, 2025

See all current drug shortages

Vendor Pricing

$0.06/gAaron Chemicals LLC
CountryHong Kong
Pack$32.00 / 500 g
Purity97%
Vendors39 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS54-85-3
PubChem CID3767
DTXSIDDTXSID8020755
FormulaC6H7N3O
Mol. Weight137.14 g/mol
SMILESC1=CN=CC=C1C(=O)NN

Data Sources

Brief citations

Isoniazid (CAS 54-85-3) https://chemicalindependence.com/chemical/54-85-3/ PubChem: 3767. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/3767 EPA TSCA Inventory: CAS 54-85-3. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA Drug Shortages: CAS 54-85-3. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293339 for CAS 54-85-3. Reporting year: 2024. https://usatrade.census.gov/