Metyrapone

Drug ingredient

CAS 54-36-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$1.3B

Top sourceChina 32%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293339 · basket

These shares come from HS customs code 293339, which covers 397 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 32%ChinaIN 15%IndiaDE 10%GermanyBE 9%BelgiumCH 8%Switzerland

Taiwan
Ukraine
Sweden
Argentina
Canada
Finland
Malta
Israel
Netherlands
Denmark
United Arab Emirates
Mexico
Brunei
Slovakia
Australia
South Africa
Poland
Latvia
Lithuania
Estonia
Slovenia
Czech Republic
Croatia
Hong Kong

4 FDA-registered drug labelers

Catalent Germany Eberbach GmbH

ESTEVE PHARMACEUTICALS, S.A.

HRA Pharma Rare Diseases

Minakem Beuvry Production

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Metopirone

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$65.32/gSigma-Aldrich (Rush Stock)

CountryGermany

Pack$65.32 / 1 g

Purity96%

Vendors25 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

24 more vendors

Vendor	Country	$/g	Pack	Purity
Sigma-Aldrich	Germany	$65.32	1 g	96%
A2B Chem LLC	United States	$76.00	1 g	95%
AA BLOCKS	United States	$84.00	1 g	95%
Aaron Chemicals LLC	Hong Kong	$117.00	5 g	95%
Cayman Europe	Estonia	$120.19	1 g	98%
Angene Chemical	China → Hong Kong	$125.20	5 g	95%
BLD Pharmatech GmbH	Germany	$160.40	5 g	95%
BLD Pharmatech Ltd.	China	$160.40	5 g	95%
Combi-Blocks, Inc.	United States	$160.40	5 g	95%
Fulfilled by Molport	Latvia	$180.00	100 mg	97%
BLD Pharmatech Co., Limited	United States	$234.00	1 g	95%
Ambeed, Inc.	United States	$234.00	1 g	95%
Molnova	China	$266.00	500 mg	99%
TargetMol Chemicals	China → United States	$294.00	500 mg	99.69%
AK Scientific, Inc.	United States	$348.00	250 mg	97%
MedKoo Biosciences, Inc	United States	$450.00	1 g	98%
MedChemExpress MCE	Sweden	$450.12	500 mg	99.83%
Labotest KG	Germany	$453.00	1000 mg	90%
TargetMol Chemicals EU	Austria	$480.00	100 mg	99.69%
Angene International Limited	United States	$676.00	250 mg	97%
Apexbio Technology LLC	United States	$1000.00	50 mg	98%
CliniSciences GmbH	Switzerland	$1161.00	50 mg	99%
AstaTech (2 weeks)	United States	$1344.00	250 mg	95%
Angene	China → Hong Kong	$2500.00	30 mg	95%

Chemical Identity

CAS54-36-4

PubChem CID4174

DTXSIDDTXSID1023314

FormulaC14H14N2O

Mol. Weight226.27 g/mol

SMILESCC(C)(C1=CN=CC=C1)C(=O)C2=CN=CC=C2

Data Sources

PubChem · compound 4174Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Metyrapone (CAS 54-36-4) https://chemicalindependence.com/chemical/54-36-4/ PubChem: 4174. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/4174 FDA National Drug Code directory: CAS 54-36-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293339 for CAS 54-36-4. Reporting year: 2024. https://usatrade.census.gov/