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Sodium salicylate

Drug ingredient

CAS 54-21-7

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

Molecular structure of 54-21-7
1 Na⁺
US productionCBI
Import value, 2024$22M
Top sourceGermany 45%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291821 · basket

EPA reports by year
2023
US production Confidential · Imports Confidential

These shares come from HS customs code 291821, which covers 14 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
DE 45%GermanyIT 16%ItalyCN 15%ChinaMX 15%MexicoIN 5%India
Domestic parents -- activity not disclosed (1)
Dooley Chemicals
25 FDA-registered drug labelers
AmerisourceBergen Drug Corp
AMOL PHARMACEUTICALS PRIVATE LIMITED
Bestmade Natural Products
Chain Drug Consortium, LLC
Chain Drug Marketing Association
Chongqing Biocare Pharmaceutical Ltd.
Clarion Brands, LLC
CVS Pharmacy, Inc
Deseret Biologicals, Inc.
Energique, Inc.
Hahnemann Laboratories, INC.
i-Health, Inc.
JQC (Huayin) Pharmaceutical Co., Ltd.
King Bio Inc.
Meijer Distribution Inc.
NaturalCare
Professional Compounding Centers of America dba PCCA
Reese Pharmaceutical Co
Rising Pharma Holdings, Inc.
Rite Aid
SALICYLATES & CHEMICALS PRIVATE LIMITED
Siddharth Carbochem Products Limited
Spectrum Laboratory Products, Inc.
Topco Associates LLC
Walgreen Company

Why It Matters

Sectors
HealthConsumer Products
Downstream Uses

Appears in 22 drug and cosmetic product listings (FDA).

  • •Natrum Salicylicum
  • •Premier Value Antibacterial Plus Urinary Pain Relief
  • •Cystex Plus
  • •URO-PAIN Dual Action Antibacterial Protection
  • •Quality Choice Antibacterial Plus Urinary Pain Relief
  • •Preferred Antibacterial Plus Urinary Pain Relief
  • •Ring HP
  • •Bestmade Natural Products BM71
Show all 22
  • •TopCare Antibacterial Plus Urinary Pain Relief
  • •Azo Urinary Tract Defense Antibacterial Protection
  • •Ear Ringing
  • •CVS Antibacterial Plus Urinary Pain Relief
  • •CVS DUAL Action PAIN Relief
  • •Walgreens Pain Relief plus UTI Bacteria Control
  • •Cystex
  • •Dizzy
  • •Walgreens Antibacterial Plus Urinary Pain Relief
  • •Ear Ring
  • •Ringstop
  • •Rite Aid Antibacterial Plus Urinary Pain Relief
  • •Meijer Antibacterial Plus Urinary Pain Relief
  • •Good Neighbor Antibacterial Plus Urinary Pain Relief
FDA Shortage Status
No FDA shortage records

Industrial Uses

  • •Preservative in Soap, Cleaning Compound, and Toilet Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.03/gBLD Pharmatech Ltd.
CountryChina
Pack$29.00 / 1 kg
Purity95%
Vendors22 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

21 more vendors
VendorCountry$/gPackPurity
BLD Pharmatech Co., LimitedUnited States$0.041 kg95%
Ambeed, Inc.United States$0.041 kg95%
BLD Pharmatech GmbHGermany$0.05500 g95%
AK Scientific SpecializedUnited States$0.051 kg98%
ChemsceneUnited States$0.051 kg—
Fluorochem EUGermany$0.061 kg98%
Fluorochem UKUnited Kingdom$0.071 kg98%
AK Scientific, Inc.United States$0.071 kg99%
Sigma-Aldrich (Rush Stock)Germany$0.135 kg99.5%
Sigma-AldrichGermany$0.135 kg99.5%
ALFA AESARGermany$0.151 kg99%
Combi-Blocks, Inc.United States$0.251 kg95%
Apexbio Technology LLCUnited States$1.4850 g99.88%
MedChemExpress MCESweden$2.6650 g99.99%
MedKoo Biosciences, IncUnited States$3.50100 g98%
AstaTech, IncUnited States$5.0025 g95%
MolnovaChina$82.00500 mg99%
TargetMol ChemicalsChina → United States$90.00500 mg99.99%
Vitas M Chemical LimitedHong Kong$163.205 g90%
Labotest KGGermany$217.805000 mg90%
Princeton BioMolecular Research (SC)United States$2900.00100 mg90%

Chemical Identity

CAS54-21-7
PubChem CID16760658
DTXSIDDTXSID5021708
FormulaC7H5NaO3
Mol. Weight160.1 g/mol
SMILESC1=CC=C(C(=C1)C(=O)[O-])O.[Na+]

Data Sources

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Brief citations

Sodium salicylate (CAS 54-21-7) https://chemicalindependence.com/chemical/54-21-7/ PubChem: 16760658. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/16760658 EPA Chemical Data Reporting: 54-21-7. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 291821 for CAS 54-21-7. Reporting year: 2024. https://usatrade.census.gov/