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Tryptophan

Drug ingredient

CAS 54-12-6

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 54-12-6
US productionNot reported
Import value, 2024$1.4B
Top sourceIreland 33%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293399 · basket

These shares come from HS customs code 293399, which covers 518 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 33%IrelandCN 26%ChinaIN 11%IndiaDE 9%GermanyIT 4%Italy
17 FDA-registered drug labelers
Ajinomoto Health & Nutrition North America Inc.
Ajinomoto Health & Nutrtion North America Inc.
Apex Energetics Inc.
B. Braun Medical Inc.
Baxter Healthcare Company
Baxter Healthcare Corporation
BioActive Nutritional, Inc.
Deseret Biologicals, Inc.
Dr. Donna Restivo DC
Energique, Inc.
Fresenius Kabi USA, LLC
Guna spa
ICU Medical Inc.
KYOWA HAKKO BIO CO., LTD.
Liddell Laboratories, Inc.
Pro Weight Loss Inc.
Professional Complementary Health Formulas

Why It Matters

Sectors
Health
Downstream Uses

Appears in 27 drug and cosmetic product listings (FDA).

  • •Aminosyn-PF
  • •Perfect Sleep
  • •Bio Viscum Phase
  • •Plenamine
  • •L-Tryptophan 7423
  • •Kabiven
  • •Clinimix
  • •Tryptophan
Show all 27
  • •Clinimix E
  • •L-Tryptophan High 7424
  • •Clinisol
  • •GUNA-Digest
  • •Sleep Tight
  • •ProSol
  • •TrophAmine
  • •Aminosyn II
  • •Metabatone
  • •Vital Skin Hair Nails
  • •E08 Bioclock Regulator
  • •Osteobios
  • •Travasol
  • •GUNA-MOOD
  • •Perikabiven
  • •Serotonin/L-Tryptophan 1548
  • •Growth Hormone Drops 2160
  • •Premasol - sulfite-free (Amino Acid)
  • •Sleep Aid
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$0.11/gAngene Chemical
CountryChina (registered: Hong Kong)
Pack$56.00 / 500 g
Purity98%
Vendors31 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

30 more vendors
VendorCountry$/gPackPurity
Aaron Chemicals LLCHong Kong$0.12500 g98%
AK Scientific SpecializedUnited States$0.201 kg98%
A2B Chem LLCUnited States$0.21500 g98%
ChemsceneUnited States$0.221 kg—
BLD Pharmatech Ltd.China$0.231 kg98%
Ambeed, Inc.United States$0.231 kg98%
BLD Pharmatech Co., LimitedUnited States$0.23500 g98%
BLD Pharmatech GmbHGermany$0.23500 g98%
AK Scientific, Inc.United States$0.251 kg98.5%
Combi-Blocks, Inc.United States$0.251 kg97%
AA BLOCKSUnited States$0.28500 g98%
Fluorochem EUGermany$0.28100 g97%
MedChemExpress MCESweden$0.64500 g99.98%
Acrotein ChemBio, Inc.United States$0.69500 g—
MedKoo Biosciences, IncUnited States$1.081 kg98%
SynthonixUnited States$1.2025 g97%
Angene International LimitedUnited States$1.43100 g97%
Fluorochem UKUnited Kingdom$1.435 g97%
Cayman EuropeEstonia$2.11100 g98%
Sigma-Aldrich (Rush Stock)Germany$2.2850 g99%
Sigma-AldrichGermany$2.2850 g99%
MolnovaChina$27.001 g99%
TargetMol ChemicalsChina → United States$29.001 g99.89%
Vitas M Chemical LimitedHong Kong$390.00500 mg90%
Maybridge, Ltd.United Kingdom$2414.30100 mg90%
Otava, Ltd.Ukraine$2724.0050 mg90%
Princeton BioMolecular Research (SC)United States$2900.00100 mg90%
ChemDiv, Inc.United States$4070.00100 mg90%
AngeneChina → Hong Kong$4266.6730 mg98%
AnalytiCon Discovery - a Division of BRAIN Biotech AGGermany$73689.0050 mg85%

Chemical Identity

CAS54-12-6
PubChem CIDNot recorded
DTXSIDDTXSID0021418
FormulaC11H12N2O2
Mol. Weight204.229 g/mol
SMILESNC(CC1=CNC2=CC=CC=C12)C(O)=O

Data Sources

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Brief citations

Tryptophan (CAS 54-12-6) https://chemicalindependence.com/chemical/54-12-6/ EPA TSCA Inventory: CAS 54-12-6. Retrieved 2026-10-04. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: CAS 54-12-6. Retrieved 2026-10-04. https://open.fda.gov/data/ndc/ US Census international trade: HS 293399 for CAS 54-12-6. Reporting year: 2024. https://usatrade.census.gov/