monophosphothiamine

Drug ingredient

CAS 532-40-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$49M

Top sourceChina 88%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293622 · basket

These shares come from HS customs code 293622, which covers 5 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 88%ChinaDE 10%GermanyJP 2%JapanIN 1%India

Poland
Austria
Denmark
Colombia
Netherlands
Canada
South Korea
United Kingdom

1 FDA-registered drug labeler

Merck KGaA

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$12.80/gSigma-Aldrich (Rush Stock)

CountryGermany

Pack$319.96 / 25 g

PurityNot recorded

Vendors10 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

9 more vendors

Vendor	Country	$/g	Pack	Purity
Sigma-Aldrich	Germany	$12.80	25 g	—
Aaron Chemicals LLC	Hong Kong	$221.00	1 g	98%
Angene Chemical	China → Hong Kong	$238.00	1 g	98%
A2B Chem LLC	United States	$276.00	1 g	98%
AstaTech (2 weeks)	United States	$325.00	1 g	95%
AA BLOCKS	United States	$360.00	1 g	98%
Labotest KG	Germany	$453.00	1000 mg	90%
MedChemExpress MCE	Sweden	$10043.00	10 mg	99.27%
Angene International Limited	United States	$20800.00	10 mg	98%

Chemical Identity

CAS532-40-1

PubChem CID10761

DTXSIDDTXSID6046397

FormulaC12H18ClN4O4PS

Mol. Weight380.79 g/mol

SMILESCC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCOP(=O)(O)O.[Cl-]

Data Sources

PubChem · compound 10761Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

monophosphothiamine (CAS 532-40-1) https://chemicalindependence.com/chemical/532-40-1/ PubChem: 10761. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/10761 FDA National Drug Code directory: CAS 532-40-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293622 for CAS 532-40-1. Reporting year: 2024. https://usatrade.census.gov/