Mitotane

Drug ingredient

CAS 53-19-0

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$108M

Top sourceChina 77%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290399 · basket

These shares come from HS customs code 290399, which covers 178 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 77%ChinaIN 7%IndiaDE 7%GermanyJP 5%JapanIT 2%Italy

Ukraine
United Kingdom
Israel
Taiwan
Russia
Hong Kong
Canada
Ireland
Latvia

5 FDA-registered drug labelers

DARMERICA, LLC

ESTEVE PHARMACEUTICALS, S.A.

HRA Pharma Rare Diseases

ISP Chemicals LLC

Medisca Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Lysodren

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$8.48/gAK Scientific Specialized

CountryUnited States

Pack$212.00 / 25 g

Purity95%

Vendors21 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

20 more vendors

Vendor	Country	$/g	Pack	Purity
Aaron Chemicals LLC	Hong Kong	$8.52	25 g	98%
Angene Chemical	China → Hong Kong	$9.16	25 g	98%
Ambeed, Inc.	United States	$10.24	25 g	99%
A2B Chem LLC	United States	$11.00	5 g	99%
AK Scientific, Inc.	United States	$11.36	25 g	98%
AA BLOCKS	United States	$12.20	5 g	99%
Angene International Limited	United States	$18.84	25 g	98%
MedKoo Biosciences, Inc	United States	$38.00	25 g	98%
TargetMol Chemicals	China → United States	$128.00	1 g	99.96%
Molnova	China	$160.00	500 mg	99%
TargetMol Chemicals EU	Austria	$176.00	500 mg	99.96%
Apexbio Technology LLC	United States	$206.00	500 mg	99.78%
Cayman Europe	Estonia	$241.57	1 g	98%
MedChemExpress MCE	Sweden	$271.04	500 mg	99.94%
AstaTech (2 weeks)	United States	$364.40	5 g	98%
Sigma-Aldrich (Rush Stock)	Germany	$401.56	250 mg	—
Sigma-Aldrich	Germany	$401.56	250 mg	—
Axon Medchem	Netherlands	$432.00	250 mg	100%
Labotest KG	Germany	$453.00	1000 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	98%

Chemical Identity

CAS53-19-0

PubChem CID4211

DTXSIDDTXSID9020372

FormulaC14H10Cl4

Mol. Weight320 g/mol

SMILESC1=CC=C(C(=C1)C(C2=CC=C(C=C2)Cl)C(Cl)Cl)Cl

Data Sources

PubChem · compound 4211Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Mitotane (CAS 53-19-0) https://chemicalindependence.com/chemical/53-19-0/ PubChem: 4211. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/4211 FDA National Drug Code directory: CAS 53-19-0. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 290399 for CAS 53-19-0. Reporting year: 2024. https://usatrade.census.gov/