Sodium D-gluconate
Drug ingredientCAS 527-07-1
This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$16M
Top sourceItaly 41%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 291816 · basket
EPA reports by year
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
These shares come from HS customs code 291816, which covers 9 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
Source Countries
Country of origin for US imports, from Census customs data (2024).
IT 41%ItalyCN 32%ChinaIN 17%IndiaDE 6%GermanyTR 2%Turkey
- Israel
- Pakistan
- Japan
EPA-registered manufacturers (5)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Fuso Chemical · JP Japan
Ecolab
Hydrite Chemical
Macdermid
Pmp Fermentation Products
Domestic parents -- activity not disclosed (6)
EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.
Brenntag
Cellmark Basic Materials
Global Chemical Resources
Nalco- An Ecolab
Polyventive
Show all 6
Starchem Usa
EPA-registered importers (16)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Basf Se · DE Germany
Jungbunzlauer Suisse Ag · CH Switzerland
Sika Ag · CH Switzerland
Basf
Chemical Distribution Network
Show all 16
Delta Carbona
Henkel
Jungbunzlauer
Mapei
Roquette America
S.C. Johnson & Son
Sika
Solenis
Valudor Products
Vivion
Wintersun International
Why It Matters
Sectors
HealthAgricultureFoodElectronicsTransportationConstructionMetals & MiningPlastics & RubberTextilesConsumer ProductsPaper & PrintingCore Chemicals
Downstream Uses
Appears in 12 drug and cosmetic product listings (FDA).
- •Isolyte S
- •Plasma-Lyte 148 (pH 7.4)
- •Normosol-R
- •Normosol-R and Dextrose
- •Electrolyte Plus
- •Multiple Electrolytes pH 5.5
- •Multiple Electrolytes pH 7.4
- •Plasma-Lyte A
Show all 12
- •Isolyte S pH 7.4
- •Bio Electrolyte
- •Physiolyte
- •Glorysmile Toothpaste.
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
Used in 17 sectors as 17 functional roles.
- •Corrosion inhibitor in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Laboratory chemicals in All Other Chemical Product and Preparation ManufacturingProcessing—repackaging
- •Adhesion/cohesion promoter in Machinery Manufacturing (2%)Processing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Transportation Equipment Manufacturing (4%)Processing—incorporation into formulation, mixture, or reaction product
- •Adhesion/cohesion promoter in Computer and Electronic Product Manufacturing (2%)Processing—incorporation into formulation, mixture, or reaction product
- •Adhesion/cohesion promoter in Electrical Equipment, Appliance, and Component Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Machinery Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Electrical Equipment, Appliance, and Component Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Adhesion/cohesion promoter in Transportation Equipment Manufacturing (34%)Processing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Computer and Electronic Product Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Adhesion/cohesion promoter in Fabricated Metal Product Manufacturing (51%)Processing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Fabricated Metal Product Manufacturing (6%)Processing—incorporation into formulation, mixture, or reaction product
- •Anti-scaling agent in Food, beverage, and tobacco product manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Food, beverage, and tobacco product manufacturing (70%)Processing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Surfactant (surface active agent) in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (85%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (15%)Processing—incorporation into formulation, mixture, or reaction product
- •Emulsifier in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (73%)Processing—incorporation into formulation, mixture, or reaction product
- •Corrosion inhibitor in All Other Basic Inorganic Chemical Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Chelating agent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (14%)Processing—incorporation into formulation, mixture, or reaction product
- •Chelating agent in Food, beverage, and tobacco product manufacturing (3%)Processing—incorporation into formulation, mixture, or reaction product
- •Chelating agent in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (11%)Processing—incorporation into formulation, mixture, or reaction product
- •Chelating agent in Non-metallic Mineral Product Manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other non-metallic mineral product manufacturing) (40%)Processing—incorporation into formulation, mixture, or reaction product
- •Plating agent in Fabricated Metal Product Manufacturing (2%)Processing—incorporation into formulation, mixture, or reaction product
- •pH regulating agent in Food, beverage, and tobacco product manufacturing (100%)Use—non-incorporative activities
- •Chemical reaction regulator in Plastics Product Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Anti-scaling agent in All Other Basic Organic Chemical Manufacturing (50%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in All Other Basic Organic Chemical Manufacturing (50%)Processing—incorporation into formulation, mixture, or reaction product
- •Etching agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Plating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Chelating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Chelating agent in Fabricated Metal Product ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Preservative in Food, beverage, and tobacco product manufacturing (50%)Processing—incorporation into article
- •Chelating agent in Wholesale and Retail Trade (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Softener and conditioner in All Other Basic Organic Chemical Manufacturing (30%)Processing—incorporation into formulation, mixture, or reaction product
- •Softener and conditioner in Paper Manufacturing (70%)Use—non-incorporative activities
- •Surface modifier in Fabricated Metal Product ManufacturingUse—non-incorporative activities
- •Corrosion inhibitor in Primary Metal Manufacturing (20%)Processing—incorporation into formulation, mixture, or reaction product
- •Flavoring and nutrient in Food, beverage, and tobacco product manufacturing (10%)Processing—incorporation into formulation, mixture, or reaction product
- •Chelating agent in Textiles, apparel, and leather manufacturing (45%)Processing—incorporation into formulation, mixture, or reaction product
Vendor Pricing
$0.02/gAngene Chemical
CountryChina (registered: Hong Kong)
Pack$10.00 / 500 g
Purity99%
Vendors18 available
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
17 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| AA BLOCKS | United States | $0.02 | 500 g | — |
| A2B Chem LLC | United States | $0.02 | 500 g | — |
| Fluorochem EU | Germany | $0.07 | 500 g | 98% |
| Sigma-Aldrich (Rush Stock) | Germany | $0.07 | 10 kg | 99% |
| Sigma-Aldrich | Germany | $0.07 | 10 kg | 99% |
| AK Scientific Specialized | United States | $0.07 | 1 kg | 98% |
| AK Scientific, Inc. | United States | $0.09 | 1 kg | 99% |
| MedChemExpress MCE | Sweden | $0.12 | 1 kg | 99.89% |
| Combi-Blocks, Inc. | United States | $0.25 | 1 kg | 98% |
| Angene International Limited | United States | $0.56 | 250 g | 98% |
| Molnova | China | $305.00 | 200 mg | 99% |
| Labotest KG | Germany | $453.00 | 1000 mg | 90% |
| AstaTech (2 weeks) | United States | $910.00 | 100 mg | 95% |
| Angene | China → Hong Kong | $4266.67 | 30 mg | 99% |
| Key Organics Ltd. | United Kingdom | $6900.00 | 10 mg | 99% |
| A2B Chem LLC (1 week) | United States | $8150.00 | 100 mg | 98% |
| AA BLOCKS (1 week) | United States | $9020.00 | 100 mg | 98% |
Chemical Identity
CAS527-07-1
PubChem CID23672301
DTXSIDDTXSID7027170
FormulaC6H11NaO7
Mol. Weight218.14 g/mol
SMILESC(C(C(C(C(C(=O)[O-])O)O)O)O)O.[Na+]
Data Sources
- EPA CompTox (DSSTox) · DTXSID7027170Retrieved 2026-04-06
- PubChem · compound 23672301Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Sodium D-gluconate (CAS 527-07-1) https://chemicalindependence.com/chemical/527-07-1/ EPA CompTox (DSSTox): DTXSID7027170. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID7027170 PubChem: 23672301. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/23672301 EPA Chemical Data Reporting: 527-07-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 527-07-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 291816 for CAS 527-07-1. Reporting year: 2024. https://usatrade.census.gov/