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Permethrin

Drug ingredient

CAS 52645-53-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 52645-53-1
US productionNot reported
Import value, 2024$554M
Top sourceGermany 28%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291620, 380891 · basket

These shares come from HS customs code 291620, 380891, which covers 81 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
DE 28%GermanyMX 14%MexicoIN 12%IndiaCN 10%ChinaJP 5%Japan
18 FDA-registered drug labelers
A-S Medication Solutions
Actavis Pharma, Inc.
Aurobindo Pharma Limited
Azico Biophore India Private Limited
Bryant Ranch Prepack
DR REDDYS LABORATORIES (EU) LTD
Encube Ethicals, Inc.
Geodis Logistics LLC
Insight Pharmaceuticals LLC
L. Perrigo Company
Northstar Rx LLC
Padagis Israel Pharmaceuticals Ltd
Preferred Pharmaceuticals Inc.
Professional Complementary Health Formulas
REMEDYREPACK INC.
Srikem Laboratories Pvt. Ltd.
Topco Associates LLC
Wavelength Enterprises LTD

Why It Matters

Sectors
Health
Downstream Uses

Appears in 7 drug and cosmetic product listings (FDA).

  • •Permethrin
  • •Elimite
  • •Topcare lice killing creme rinse
  • •Nix
  • •Airline Pesticide Detox 6030
  • •Nix Lice Killing Creme Rinse
  • •good sense lice killing creme rinse
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS52645-53-1
PubChem CID40326
DTXSIDDTXSID8022292
FormulaC21H20Cl2O3
Mol. Weight391.3 g/mol
SMILESCC1(C(C1C(=O)OCC2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C

Data Sources

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Brief citations

Permethrin (CAS 52645-53-1) https://chemicalindependence.com/chemical/52645-53-1/ PubChem: 40326. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/40326 FDA National Drug Code directory: CAS 52645-53-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 291620,380891 for CAS 52645-53-1. Reporting year: 2024. https://usatrade.census.gov/