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Buprenorphine

Drug ingredient

CAS 52485-79-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 52485-79-7
US productionNot reported
Import value, 2024$103M
Top sourceAustralia 31%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293911 · basket

These shares come from HS customs code 293911, which covers 13 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
AU 31%AustraliaGB 27%United KingdomCZ 19%Czech RepublicDE 14%GermanyES 5%Spain
28 FDA-registered drug labelers
Alvogen Inc.
Amneal Pharmaceuticals NY LLC
Arevipharma GmbH
Aveva Drug Delivery Systems Inc.
Braeburn Inc.
Bryant Ranch Prepack
Indivior Inc.
Indivior UK Limited
INGENUS PHARMACEUTICALS, LLC
Janssen Pharmaceutica NV
Janssen Pharmaceutical Sciences Unlimited Company
Lannett Company, Inc.
LTS Therapy Systems, LLC
Macfarlan Smith Limited
Medisca Inc
Noramco, LLC
PCAS
Purdue Pharma LP
Rhodes Pharmaceuticals L.P.
Siegfried AG
Siegfried PharmaChemikalien Minden Gmbh
Siegfried USA, LLC
SpecGx LLC
SUN PHARMACEUTICAL INDUSTRIES, INC.
TAPI Czech Industries s.r.o.
Teva Czech Industries s.r.o
Teva Pharmaceuticals USA, Inc.
Veranova, L.P.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 6 drug and cosmetic product listings (FDA).

  • •Sublocade
  • •Buprenorphine
  • •Butrans
  • •buprenorphine transdermal system
  • •Brixadi
  • •Buprenorphine and Naloxone
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS52485-79-7
PubChem CID644073
DTXSIDDTXSID2022705
FormulaC29H41NO4
Mol. Weight467.6 g/mol
SMILESCC(C)(C)C(C)(C1CC23CCC1(C4C25CCN(C3CC6=C5C(=C(C=C6)O)O4)CC7CC7)OC)O

Data Sources

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Brief citations

Buprenorphine (CAS 52485-79-7) https://chemicalindependence.com/chemical/52485-79-7/ PubChem: 644073. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/644073 FDA National Drug Code directory: CAS 52485-79-7. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293911 for CAS 52485-79-7. Reporting year: 2024. https://usatrade.census.gov/