1,3-Bis(3-(dimethylamino)propyl)urea

CAS 52338-87-1

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$667M

Top sourceChina 18%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292419, 381590 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 292419, 381590, which covers 214 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 18%ChinaDE 17%GermanyIN 13%IndiaGB 9%United KingdomIT 8%Italy

Spain
Austria
Hungary
South Africa
Poland
Australia
Egypt
Ukraine
Israel
Lithuania
Greece
Taiwan
Slovenia
Finland
Ireland
Turkey
Uruguay
Vietnam
Norway
Latvia
Colombia

EPA-registered manufacturers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Innospec

Mcgean-Roh

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Evonik

EPA-registered importers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Columbia Chemical

Why It Matters

Sectors

TransportationConsumer ProductsPaints & CoatingsCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 4 sectors as 4 functional roles.

•Chemical reaction regulator in Transportation Equipment Manufacturing (25%)Processing—incorporation into formulation, mixture, or reaction product
•Chemical reaction regulator in Furniture and Related Product Manufacturing (25%)Processing—incorporation into formulation, mixture, or reaction product
•Propellants, non-motive (blowing agents) in Furniture and Related Product Manufacturing (25%)Processing—incorporation into formulation, mixture, or reaction product
•Propellants, non-motive (blowing agents) in Transportation Equipment Manufacturing (25%)Processing—incorporation into formulation, mixture, or reaction product
•Intermediate in All Other Basic Inorganic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Hardener in All Other Basic Inorganic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Intermediate in Paint and Coating ManufacturingProcessing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.28/gA2B Chem LLC

CountryUnited States

Pack$284.00 / 1 kg

Purity97%

Vendors15 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

14 more vendors

Vendor	Country	$/g	Pack	Purity
AA BLOCKS	United States	$0.32	1 kg	97%
Combi-Blocks, Inc.	United States	$0.35	1 kg	97%
Chemscene	United States	$0.39	1 kg	—
BLD Pharmatech Ltd.	China	$0.40	1 kg	97%
Ambeed, Inc.	United States	$0.40	1 kg	97%
Aaron Chemicals LLC	Hong Kong	$0.47	500 g	97%
BLD Pharmatech Co., Limited	United States	$0.49	500 g	97%
BLD Pharmatech GmbH	Germany	$0.49	500 g	97%
Angene Chemical	China → Hong Kong	$0.51	500 g	97%
Angene International Limited	United States	$0.86	500 g	95%
Fluorochem EU	Germany	$1.57	10 g	95%
Synthonix	United States	$1.60	25 g	97%
AstaTech (2 weeks)	United States	$31.60	5 g	95%
Angene	China → Hong Kong	$4266.67	30 mg	97%

Chemical Identity

CAS52338-87-1

PubChem CID104163

DTXSIDDTXSID4068741

FormulaC11H26N4O

Mol. Weight230.35 g/mol

SMILESCN(C)CCCNC(=O)NCCCN(C)C

Data Sources

EPA CompTox (DSSTox) · DTXSID4068741Retrieved 2026-04-06
PubChem · compound 104163Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

1,3-Bis(3-(dimethylamino)propyl)urea (CAS 52338-87-1) https://chemicalindependence.com/chemical/52338-87-1/ EPA CompTox (DSSTox): DTXSID4068741. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID4068741 PubChem: 104163. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/104163 EPA Chemical Data Reporting: 52338-87-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 52338-87-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292419,381590 for CAS 52338-87-1. Reporting year: 2024. https://usatrade.census.gov/