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apiole (parsley)

Drug ingredient

CAS 523-80-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 523-80-8
US productionNot reported
Import value, 2024$3.5B
Top sourceIreland 57%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293299 · basket

These shares come from HS customs code 293299, which covers 229 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 57%IrelandNL 24%NetherlandsCH 8%SwitzerlandCN 5%ChinaIT 2%Italy
3 FDA-registered drug labelers
Deseret Biologicals, Inc.
Dr. Donna Restivo DC
Professional Complementary Health Formulas

Why It Matters

Sectors
Health
Downstream Uses

Appears in 7 drug and cosmetic product listings (FDA).

  • •Young Again
  • •Apiol 1503
  • •HGH Vitality
  • •Bio Thalamus Phase
  • •Chronagesic
  • •High Vitality
  • •Allermilk
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS523-80-8
PubChem CID10659
DTXSIDDTXSID4041236
FormulaC12H14O4
Mol. Weight222.24 g/mol
SMILESCOC1=C2C(=C(C(=C1)CC=C)OC)OCO2

Data Sources

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Brief citations

apiole (parsley) (CAS 523-80-8) https://chemicalindependence.com/chemical/523-80-8/ PubChem: 10659. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/10659 EPA TSCA Inventory: CAS 523-80-8. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293299 for CAS 523-80-8. Reporting year: 2024. https://usatrade.census.gov/