trimipramine maleate

Drug ingredient

CAS 521-78-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$1.4B

Top sourceIreland 33%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293399 · basket

These shares come from HS customs code 293399, which covers 518 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 33%IrelandCN 26%ChinaIN 11%IndiaDE 9%GermanyIT 4%Italy

Taiwan
Poland
Canada
Ivory Coast
Greece
Hungary
Indonesia
Latvia
Belgium
Slovakia
Czech Republic
Austria
Netherlands
Finland
Denmark
Croatia
Australia
South Africa
Sweden
Hong Kong
Malta
Singapore
Lithuania
Malaysia
Oman
Serbia

5 FDA-registered drug labelers

Breckenridge Pharmaceutical, Inc.

Bryant Ranch Prepack

Elite Laboratories, Inc.

Lundbeck Pharmaceuticals Italy S.p.A.

Sanofi Winthrop Industrie

Why It Matters

Sectors

Health

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•Trimipramine Maleate
•Trimipramine

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$18.80/gAA BLOCKS

CountryUnited States

Pack$94.00 / 5 g

Purity99%

Vendors2 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

1 more vendor

Vendor	Country	$/g	Pack	Purity
Aaron Chemicals LLC	Hong Kong	$84.20	5 g	99%

Chemical Identity

CAS521-78-8

PubChem CID5282318

DTXSIDDTXSID2045315

FormulaC24H30N2O4

Mol. Weight410.5 g/mol

SMILESCC(CN1C2=CC=CC=C2CCC3=CC=CC=C31)CN(C)C.C(=CC(=O)O)C(=O)O

Data Sources

PubChem · compound 5282318Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

trimipramine maleate (CAS 521-78-8) https://chemicalindependence.com/chemical/521-78-8/ PubChem: 5282318. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5282318 FDA National Drug Code directory: CAS 521-78-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293399 for CAS 521-78-8. Reporting year: 2024. https://usatrade.census.gov/