Diosmin

Drug ingredient

CAS 520-27-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$7M

Top sourceChina 79%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293810 · narrow

These shares come from HS customs code 293810, which covers 3 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 79%ChinaES 19%SpainBR 2%Brazil

Japan
Canada

1 FDA-registered drug labeler

Puretek Corporation

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Bruselix Bruising

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$0.32/gCombi-Blocks, Inc.

CountryUnited States

Pack$315.00 / 1 kg

Purity96%

Vendors32 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

31 more vendors

Vendor	Country	$/g	Pack	Purity
A2B Chem LLC	United States	$0.32	500 g	95%
AA BLOCKS	United States	$0.34	1 kg	95%
Aaron Chemicals LLC	Hong Kong	$0.37	500 g	95%
Ambeed, Inc.	United States	$0.38	500 g	95%
BLD Pharmatech Co., Limited	United States	$0.38	500 g	95%
BLD Pharmatech Ltd.	China	$0.38	500 g	95%
Angene Chemical	China → Hong Kong	$0.42	500 g	98%
BLD Pharmatech GmbH	Germany	$0.50	100 g	95%
AK Scientific Specialized	United States	$1.10	100 g	95%
AstaTech, Inc	United States	$1.32	100 g	95%
Angene International Limited	United States	$2.74	100 g	98%
AK Scientific, Inc.	United States	$4.06	100 g	98%
Cayman Europe	Estonia	$7.33	25 g	90%
Interbioscreen	Hong Kong	$25.50	10 g	95%
MedKoo Biosciences, Inc	United States	$30.00	25 g	98%
TargetMol Chemicals	China → United States	$338.00	500 mg	98.14%
Vitas M Chemical Limited	Hong Kong	$390.00	500 mg	90%
Labotest KG	Germany	$453.00	1000 mg	90%
MedChemExpress MCE	Sweden	$525.14	500 mg	99.51%
Molnova	China	$650.00	100 mg	99%
ChemNorm	China	$1300.00	20 mg	98%
Chengdu Biopurify Phytochemicals Ltd.	China	$1400.00	100 mg	98%
ChemFaces	China	$1500.00	20 mg	98%
Sigma-Aldrich (Rush Stock)	Germany	$1783.87	300 mg	—
Sigma-Aldrich	Germany	$1783.87	300 mg	—
Apexbio Technology LLC	United States	$2500.00	20 mg	98.07%
Otava, Ltd. (2 weeks)	Ukraine	$2724.00	50 mg	90%
Princeton BioMolecular Research (SC)	United States	$2900.00	100 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	98%
Key Organics Ltd.	United Kingdom	$6900.00	10 mg	98%
AnalytiCon Discovery - a Division of BRAIN Biotech AG	Germany	$73652.70	100 mg	85%

Chemical Identity

CAS520-27-4

PubChem CID5281613

DTXSIDDTXSID4045892

FormulaC28H32O15

Mol. Weight608.5 g/mol

SMILESCC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC(=C(C=C5)OC)O)O)O)O)O)O)O)O

Data Sources

PubChem · compound 5281613Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Diosmin (CAS 520-27-4) https://chemicalindependence.com/chemical/520-27-4/ PubChem: 5281613. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5281613 FDA National Drug Code directory: CAS 520-27-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293810 for CAS 520-27-4. Reporting year: 2024. https://usatrade.census.gov/