Prednisolone acetate

Drug ingredient

CAS 52-21-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 52-21-1
US productionNot reported
Import value, 2024$154M
Top sourceItaly 60%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293729 · basket

These shares come from HS customs code 293729, which covers 57 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IT 60%ItalyES 14%SpainCN 11%ChinaDE 6%GermanyAT 2%Austria
18 FDA-registered drug labelers
A-S Medication Solutions
Allergan, Inc.
Amneal Pharmaceuticals NY LLC
Asclemed USA, Inc.
EUROAPI FRANCE
Farmabios S.p.A.
Henan Lihua Pharmaceutical Co Ltd
Lupin Pharmaceuticals, Inc.
Medisca Inc.
NuCare Pharmaceuticals,Inc.
Pacific Pharma, Inc.
Redpharm Drug
Sandoz Inc
Spectrum Laboratory Products, Inc.
Sportpharm, Inc. dba Sportpharm
Symbiotec Pharmalab Limited
SYMBIOTICA SPECIALITY INGREDIENTS SDN.BHD
zhejiang xianju pharmaceutical co., Ltd.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

  • •Prednisolone Acetate
  • •PRED MILD
  • •PRED Forte
FDA Shortage Status
No Shortage

Vendor Pricing

$3.56/gAaron Chemicals LLC
CountryHong Kong
Pack$356.00 / 100 g
Purity98%
Vendors25 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS52-21-1
PubChem CID5834
DTXSIDDTXSID3023502
FormulaC23H30O6
Mol. Weight402.5 g/mol
SMILESCC(=O)OCC(=O)C1(CCC2C1(CC(C3C2CCC4=CC(=O)C=CC34C)O)C)O

Data Sources

Brief citations

Prednisolone acetate (CAS 52-21-1) https://chemicalindependence.com/chemical/52-21-1/ PubChem: 5834. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5834 FDA National Drug Code directory: CAS 52-21-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 52-21-1. Retrieved 2026-06-13. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293729 for CAS 52-21-1. Reporting year: 2024. https://usatrade.census.gov/