Fluorescein sodium

Drug ingredient

CAS 518-47-8

Companies reported imports and no US production of this drug ingredient to EPA for 2023.

US productionZero

Import value, 2024$14M

Import volume35.7K lb

Import dependency100%

Top sourceIndia 21%

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Fluorescein sodium · US import value by year

2013: $13M · Peak 2014: $17M · 2024: $14M · 2025: $15M

Where It Comes From

Customs basis: HS 320490 · basket

EPA reports by year

2023: US production Zero · Imports 35.7K lb

These shares come from HS customs code 320490, which covers 9 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IN 21%IndiaKR 18%South KoreaGB 13%United KingdomDE 10%GermanyBE 8%Belgium

Australia
Poland
Mexico
Finland
Peru
Czech Republic
Netherlands

EPA-registered importers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Target

11 FDA-registered drug labelers

Alcon, Inc.

Altaire Pharmaceuticals Inc.

Bausch & Lomb Americas Inc.

Bausch & Lomb Incorporated

HF Acquisition Co LLC, DBA HealthFirst

Icrom S.r.l.

Long Grove Pharmaceuticals, LLC

MACSEN DRUGS

Nomax Inc.

Oceanside Pharmaceuticals

Vistamerica USA

Why It Matters

Sectors

Health

Downstream Uses

Appears in 9 drug and cosmetic product listings (FDA).

•Dry Eye Test
•Fluorescein Sodium and Benoxinate Hydrochloride
•AK-Fluor
•Fluorescein Sodium and Proparacaine Hydrochloride
•Fluorescite
•GloStrips
•Altafluor
•Fluorescein

Show all 9

•C20H10Na2O5 Fluorescein Sodium Ophthalmic Strips

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$0.34/gAK Scientific, Inc.

CountryUnited States

Pack$172.00 / 500 g

Purity98%

Vendors3 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

2 more vendors

Vendor	Country	$/g	Pack	Purity
TargetMol Chemicals	China → United States	$57.00	1 g	97.55%
Labotest KG	Germany	$453.00	1000 mg	90%

Chemical Identity

CAS518-47-8

PubChem CID10608

DTXSIDDTXSID9025328

FormulaC20H10Na2O5

Mol. Weight376.3 g/mol

SMILESC1=CC=C(C(=C1)C2=C3C=CC(=O)C=C3OC4=C2C=CC(=C4)[O-])C(=O)[O-].[Na+].[Na+]

Data Sources

PubChem · compound 10608Retrieved 2026-04-07
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Fluorescein sodium (CAS 518-47-8) https://chemicalindependence.com/chemical/518-47-8/ PubChem: 10608. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/10608 EPA Chemical Data Reporting: 518-47-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 320490 for CAS 518-47-8. Reporting year: 2024. https://usatrade.census.gov/