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Podofilox

Drug ingredient

CAS 518-28-5

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 518-28-5
US productionNot reported
Import value, 2024$286M
Top sourceChina 48%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293220 · basket

These shares come from HS customs code 293220, which covers 151 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 48%ChinaIN 15%IndiaJP 7%JapanGB 7%United KingdomCH 7%Switzerland
6 FDA-registered drug labelers
Allergan, Inc.
Analytecon SA
Padagis US LLC
Pfanstiehl, Inc.
PolyCarbon Industries, Inc.
WAVELENGTH ENTERPRISES LTD

Why It Matters

Sectors
Health
Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

  • •Podofilox
  • •Condylox
FDA Shortage Status
No Shortage
Shortage History
  • to be discontinued

    Podofilox Topical Gel

    Shortage listed since January 28, 2026

See all current drug shortages

Vendor Pricing

$0.91/gFluorochem EU
CountryGermany
Pack$90.75 / 100 g
Purity98%
Vendors41 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

40 more vendors
VendorCountry$/gPackPurity
Aaron Chemicals LLCHong Kong$2.17100 g98%
Angene ChemicalChina → Hong Kong$2.34100 g98%
Combi-Blocks, Inc.United States$2.80100 g98%
A2B Chem LLCUnited States$3.02100 g98%
AA BLOCKSUnited States$3.18100 g98%
AK Scientific SpecializedUnited States$4.20100 g95%
AK Scientific, Inc.United States$5.76100 g98%
MedKoo Biosciences, IncUnited States$5.90500 g98%
MedChemExpress MCESweden$11.37100 g99.92%
TargetMol ChemicalsChina → United States$52.502 g99.73%
Angene International LimitedUnited States$63.001 g98%
ChemDiv, Inc.United States$75.0025 g90%
TargetMol Chemicals USUnited States$78.001 g99.73%
TargetMol Chemicals EUAustria$116.00500 mg99.73%
MolnovaChina$118.00500 mg99%
EximedUkraine$144.005 g95%
InterbioscreenHong Kong$150.0010 g95%
Cayman EuropeEstonia$411.741 g98%
Otava, Ltd.Ukraine$450.001 g95%
Labotest KGGermany$453.001000 mg90%
ChemNormChina$750.0020 mg98%
Axon MedchemNetherlands$960.0050 mg98%
Combi-Blocks (back-ordered)United States$1008.001 g95%
CliniSciences GmbHSwitzerland$1161.0050 mg98%
Sigma-Aldrich (Rush Stock)Germany$1442.2050 mg—
Sigma-AldrichGermany$1442.2050 mg—
ChemFacesChina$1500.0020 mg98%
Ambeed, Inc.United States$1640.00250 mg98%
Apexbio Technology LLCUnited States$2500.0020 mg99.68%
Otava, Ltd. (2 weeks)Ukraine$2724.0050 mg95%
Fulfilled by MolportLatvia$3800.005 mg99.6%
AngeneChina → Hong Kong$4266.6730 mg98%
Key Organics Ltd.United Kingdom$6900.0010 mg97%
Vitas M Chemical LimitedHong Kong$13030.8910 μmol90%
Princeton BioMolecular Research (SC)United States$18000.005 mg90%
TimTec, LLC (back-ordered)United States$33333.3315 mg94%
A2B Chem LLC (2 weeks)United States$36350.0020 mg98%
AA BLOCKS (2 weeks)United States$37350.0020 mg98%
AstaTech, IncUnited States$59920.0025 mg98%
AnalytiCon Discovery - a Division of BRAIN Biotech AGGermany$73652.70100 mg85%

Chemical Identity

CAS518-28-5
PubChem CID10607
DTXSIDDTXSID3045645
FormulaC22H22O8
Mol. Weight414.4 g/mol
SMILESCOC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O

Data Sources

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Brief citations

Podofilox (CAS 518-28-5) https://chemicalindependence.com/chemical/518-28-5/ PubChem: 10607. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/10607 FDA National Drug Code directory: CAS 518-28-5. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 518-28-5. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293220 for CAS 518-28-5. Reporting year: 2024. https://usatrade.census.gov/