sennosides
Drug ingredientCAS 517-43-1
This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.
US productionNot reported
Import value, 2024$296M
Top sourceChina 71%
This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.
Why supply is unknownProduction is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 293890 · basket
These shares come from HS customs code 293890, which covers 25 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
Source Countries
Country of origin for US imports, from Census customs data (2024).
CN 71%ChinaMY 11%MalaysiaBR 3%BrazilKR 2%South KoreaCL 2%Chile
- United Kingdom
- Canada
- Guatemala
- Bulgaria
- New Zealand
- Thailand
- Turkey
- Belgium
- Sweden
- Netherlands
- Austria
- Israel
- Mexico
- Australia
- Ecuador
- Finland
- Slovakia
- Hong Kong
- Romania
- Colombia
- Taiwan
116 FDA-registered drug labelers
AARNA USA INC.
Advanced Rx LLC
Akron Pharma Inc.
Alchem International Private Ltd
Aldama Pharmaceuticals, Inc
Allegiant Health
Alps Pharmaceutical Ind. Co., Ltd.
American Health Packaging
AmerisourceBergen (Good Neighbor Pharmacy) 46122
AMOL PHARMACEUTICALS PRIVATE LIMITED
ARMY AND AIR FORCE EXCHANGE SERVICE
Asclemed USA, Inc.
ATLANTIC BIOLOGICALS CORP.
Atlantis Consumer Healthcare, Inc.
AVPAK
Basic Drugs, Inc.
Belleview Biosciences
Best Choice (Valu Merchandisers Company)
BETTER LIVING BRANDS LLC.
Bi-Mart
Brainstorm Industries LLC
Bryant Ranch Prepack
C.D.M.A., Inc.
CARDINAL HEALTH
Cardinal Health 107, LLC
Cardinal Health 110, LLC. DBA Leader
CARDINAL HEALTH, 110 DBA LEADER
Care One (Retail Business Services, LLC.)
CHAIN DRUG MARKETING ASSOCIATION INC
Contract Pharmacal Corp.
CVS HEALTH
CVS PHARMACY
CVS Pharmacy, Inc
Discount Drug Mart, Inc
Dolgencorp Inc.
Dolgencorp, Inc. (DOLLAR GENERAL & REXALL)
DOLGENCORP, LLC
EQUATE (Wal-Mart Stores, Inc.) (see also WAL-MART INC)
Everpharm LLC
Family Dollar (FAMILY WELLNESS)
Family Dollar Services Inc
Farmacias De Similares TX LLC
Geri-Care Pharmaceutical Corp
Globela Pharma Pvt Ltd
GOOD SENSE
Good Sense (Geiss, Destin & Dunn, Inc.)
Granulation Technology, Inc.
Granules USA Inc
Guardian Drug Company
H E B
Haleon US Holdings LLC
Health Plus Inc.
HealthLife of USA LLC
Heartland Pharma Co.
HHH Pharmaceuticals
K PATEL PHYTO EXTRACTIONS PRIVATE LIMITED
Kesin Pharma Corporation
Kothari Phytochemicals International
KROGER
KROGER COMPANY
L.N.K. International, Inc.
LEADER/ Cardinal Health 110, Inc.
Llorens Pharmaceutical International Division, Inc.
Magno-Humphries, Inc.
Major Pharmaceuticals
Marc Glassman, Inc.
Marlex Pharmaceuticals Inc
MEDGEL PRIVATE LIMITED
Meijer Distribution, Inc.
MEIJER, INC.
Method Pharmaceuticals
Morepen Laboratories Limited
NCS HealthCare of KY, LLC dba Vangard Labs
NUVICARE LLC
OPMX LLC
P & L Development, LLC
PAI Holdings, LLC dba PAI Pharma
Patrin Pharma, Inc.
Pharbest Pharmaceuticals, Inc.
Pioneer Life Sciences, LLC
Preferred Pharmaceuticals Inc.
Prodose, Inc.
Proficient Rx LP
QUALITY CHOICE (Chain Drug Marketing Association)
Reliable 1 Laboratories LLC
Rising Pharma Holdings, Inc.
Rite Aid Corporation
RMT HEALTH LLC
RUGBY LABORATORIES
SAB HERBALS AND NUTRACEUTICALS
Safecor Health, LLC
Safeway, Inc.
Sato Pharmaceutical Co., Ltd.
SHASHI PHYTOCHEMICAL INDUSTRIES
Shield Pharmaceuticals Corp
SOFTGEL HEALTHCARE PRIVATE LIMITED
Softgel Healthcare Pvt Ltd
STRATEGIC SOURCING SERVICES LLC
TARGET CORPORATION
TCB USA Corporation
The Kroger Co.
TIME CAP LABORATORIES, INC
TOP CARE (Topco Associates LLC)
Topco Associates
TOPCO ASSOCIATES LLC
Ulai Health LLC
United Natural Foods, Inc. dba UNFI
Valu Merchandisers Company
Village Pharma
Vovantis Laboratories Private Limited
Wal-Mart Stores Inc
WALGREENS
WALGREENS CO.
WALMART INC.
WALMART INC. (see also Equate)
WinCo Foods, LLC
Why It Matters
Sectors
Health
Downstream Uses
Appears in 78 drug and cosmetic product listings (FDA).
- •Senna-S
- •Senna Syrup
- •Gencare-Senna-S Softgel
- •Senna Laxative
- •Senna
- •Maximum Strength Senna Laxative
- •Natural Senna Laxative
- •Stool Softener Laxative
Show all 78
- •Stool Softener and Stimulant Laxative
- •Sennosides
- •Senna UD
- •Stool Softener Plus Stimulant Laxative
- •Stool Softener-Stimulant Laxative
- •Chocolate Laxative Regular strength, Sennosides Stimulant Laxative, equate
- •Sankaijo
- •Laxative
- •Senokot
- •Walgreens Senna Laxative
- •Colon Detox
- •Leader Regular Strength Chocolate Laxative sennosides
- •Stimulant Laxative Plus Stool Softener
- •Senna Liquid
- •Sennosides, Docusate Sodium
- •Docusate Sodium and Sennosides
- •Chocolated Laxative Regular Strength Sennosides Stimulant Laxative, DG health
- •Stool Softener Laxative Plus Stimulant
- •Geri-kot
- •GeriCare Senna Syrup
- •Sennosides and Docusate Sodium
- •Laxative Regular Strength
- •Senna Natural Relief
- •Vegetable Laxative
- •EX-LAX Regular Strength Chocolated Stimulant Laxative
- •HEB Maximum strength Laxative pills
- •CVS Health Stool Softener Plus stimulant laxative Softgel
- •Drug Mart Vegetable Laxative plus Stool Softener
- •Senna Plus
- •Chocolated Laxative Regular Strength Sennosides Stimulant Laxative TopCare health
- •Chocolated Laxative
- •Docuzen
- •Senna-Tabs
- •EX-LAX Maximum Strength Stimulant Laxative
- •Stool Softener
- •CVS Senna Laxative
- •Senna S Orange
- •EX-LAX Regular Strength Stimulant Laxative
- •Senexon-S
- •Equaline Regular Strength Chocolated Stimulant Laxative
- •Senna WITH Docusate Sodium
- •Senna-S Softgel
- •Maximum Strength Laxative
- •Laxative and Stool Softener
- •Super Colon Cleanse
- •Stool Softener with Laxative
- •Kroger Senna Laxative Regular Strength
- •Laxative Senna
- •Colace
- •Senna Lax
- •Perdiem
- •Senna-S Laxative WITH Stool Softener
- •Dr Simi Regular Strength Sennosides 8.6mg
- •Maximum Strength Laxative Pills
- •Natural Vegetable Laxative and Stool Softener
- •Vegetable Laxative and Stool Softner
- •Natural Laxative
- •Drug Mart Stool Softener plus Stimulant Laxative
- •Stool Softener with Stimulant Laxative
- •Laxative Stool Softener
- •Laxative Docusate Sodium with Senna
- •Stool Softener Plus Stimulant
- •Sool Softener Laxative
- •Stool Softener plus Laxative
- •Senokot-S
- •Healix Senna-S
- •Meijer Senna Laxative Regular Strength
- •Sennosides Natural Laxative
- •Exchange select
- •Chocolated Laxative Regular Strength Sennosides Stimulant Laxative, Best Choice
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Chemical Identity
CAS517-43-1
PubChem CID5199
DTXSIDDTXSID20859118
FormulaC42H38O20
Mol. Weight862.7 g/mol
SMILESC1=CC2=C(C(=C1)OC3C(C(C(C(O3)CO)O)O)O)C(=O)C4=C(C2C5C6=C(C(=CC=C6)OC7C(C(C(C(O7)CO)O)O)O)C(=O)C8=C5C=C(C=C8O)C(=O)O)C=C(C=C4O)C(=O)O
Data Sources
- PubChem · compound 5199Retrieved 2026-04-07
- FDA National Drug Code directoryRetrieved 2026-04-25
- FDA National Drug Code directoryRetrieved 2026-04-07
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
sennosides (CAS 517-43-1) https://chemicalindependence.com/chemical/517-43-1/ PubChem: 5199. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5199 FDA National Drug Code directory: CAS 517-43-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293890 for CAS 517-43-1. Reporting year: 2024. https://usatrade.census.gov/