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Valine

Drug ingredient

CAS 516-06-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 516-06-3
US productionNot reported
Import value, 2024$503M
Top sourceChina 25%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292249 · basket

These shares come from HS customs code 292249, which covers 170 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 25%ChinaIN 17%IndiaSG 13%SingaporeIT 9%ItalyCH 7%Switzerland
18 FDA-registered drug labelers
Ajinomoto Health & Nutrition North America Inc.
B. Braun Medical Inc.
Baxter Healthcare Company
Baxter Healthcare Corporation
BioActive Nutritional, Inc.
Deseret Biologicals, Inc.
Energique, Inc.
Fresenius Kabi USA, LLC
Guna spa
ICU Medical Inc.
KYOWA HAKKO BIO CO., LTD.
Liddell Laboratories, Inc.
Nutritional Specialties, Inc.
Professional Complementary Health Formulas
Professional Compounding Centers of America
Shanghai Ajinomoto Amino Acid Co., Ltd.
Shanghai Plumino Amino Acid Co., Ltd.
Temple Health Nutrition, LLC

Why It Matters

Sectors
Health
Downstream Uses

Appears in 24 drug and cosmetic product listings (FDA).

  • •Aminosyn-PF
  • •Electrolyte Plus
  • •Strength F
  • •Plenamine
  • •Kabiven
  • •Clinimix
  • •L-Valine High 7430
  • •Clinimix E
Show all 24
  • •L-Valine 7429
  • •Clinisol
  • •Cardio Tonic
  • •Strength M
  • •ProSol
  • •TrophAmine
  • •TH-101
  • •Aminosyn II
  • •Metabatone
  • •Vital Skin Hair Nails
  • •Osteobios
  • •Travasol
  • •Recovatone
  • •Perikabiven
  • •Metab
  • •Premasol - sulfite-free (Amino Acid)
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$0.01/gAaron Chemicals LLC
CountryHong Kong
Pack$15.00 / 1 kg
Purity99%
Vendors22 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

21 more vendors
VendorCountry$/gPackPurity
Angene ChemicalChina → Hong Kong$0.02500 g99%
A2B Chem LLCUnited States$0.031 kg97%
AA BLOCKSUnited States$0.031 kg98%
ChemsceneUnited States$0.091 kg—
Fluorochem EUGermany$0.09500 g98%
BLD Pharmatech Co., LimitedUnited States$0.101 kg98%
BLD Pharmatech Ltd.China$0.101 kg98%
Ambeed, Inc.United States$0.101 kg98%
MedChemExpress MCESweden$0.141 kg98%
Sigma-Aldrich (Rush Stock)Germany$0.1510 kg97%
Sigma-AldrichGermany$0.1510 kg97%
Acrotein ChemBio, Inc.United States$0.151 kg—
AK Scientific SpecializedUnited States$0.221 kg97%
Combi-Blocks, Inc.United States$0.251 kg98%
AK Scientific, Inc.United States$0.281 kg99%
Angene International LimitedUnited States$0.28500 g98%
Labotest KGGermany$217.805000 mg90%
MolnovaChina$380.00100 mg99%
Otava, Ltd.Ukraine$460.00250 mg95%
AngeneChina → Hong Kong$4266.6730 mg99%
TimTec, LLC (back-ordered)United States$32000.0015 mg94%

Chemical Identity

CAS516-06-3
PubChem CIDNot recorded
DTXSIDDTXSID70859522
FormulaC5H11NO2
Mol. Weight117.148 g/mol
SMILESCC(C)C(N)C(O)=O

Data Sources

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Brief citations

Valine (CAS 516-06-3) https://chemicalindependence.com/chemical/516-06-3/ EPA TSCA Inventory: CAS 516-06-3. Retrieved 2026-10-04. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: CAS 516-06-3. Retrieved 2026-10-04. https://open.fda.gov/data/ndc/ US Census international trade: HS 292249 for CAS 516-06-3. Reporting year: 2024. https://usatrade.census.gov/