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Dihydroergotamine

Drug ingredient

CAS 511-12-6

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 511-12-6
US productionNot reported
Import value, 2024$6M
Top sourceCzech Republic 36%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293969 · basket

These shares come from HS customs code 293969, which covers 7 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CZ 36%Czech RepublicJP 30%JapanIT 17%ItalyCN 15%ChinaCA 1%Canada
1 FDA-registered drug labeler
Teva Czech Industries s.r.o

Why It Matters

Sectors
Health
Downstream UsesNot recorded
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS511-12-6
PubChem CID10531
DTXSIDDTXSID6045614
FormulaC33H37N5O5
Mol. Weight583.7 g/mol
SMILESCC1(C(=O)N2C(C(=O)N3CCCC3C2(O1)O)CC4=CC=CC=C4)NC(=O)C5CC6C(CC7=CNC8=CC=CC6=C78)N(C5)C

Data Sources

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Brief citations

Dihydroergotamine (CAS 511-12-6) https://chemicalindependence.com/chemical/511-12-6/ PubChem: 10531. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/10531 FDA National Drug Code directory: CAS 511-12-6. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293969 for CAS 511-12-6. Reporting year: 2024. https://usatrade.census.gov/