epinephrine
Drug ingredientActive ShortageCAS 51-43-4
This drug ingredient is in active FDA shortage. At least one manufacturer cannot meet demand.
This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.
Why supply is unknownProduction is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 293790 · basket
These shares come from HS customs code 293790, which covers 10 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
- Switzerland
- Finland
- Sweden
- Canada
- South Africa
- Netherlands
- Hungary
- Spain
- Argentina
- Israel
- Ecuador
- South Korea
- Poland
75 FDA-registered drug labelers
Why It Matters
Appears in 115 drug and cosmetic product listings (FDA).
- •Adrenalin
- •Lidocaine Hydrochloride and Epinephrine
- •Epinephrine
- •Auvi-Q
- •Weight Loss Support Plus Female Balance
- •Weight Loss Support Plus Adrenal
- •Primatene Mist
- •Chronic Fatigue Therapy
Show all 115
- •FCS CP
- •Neuro II
- •Adrenal Support
- •BP Reg
- •Rage
- •Emotional Detox and Drainage
- •Adrenalinum
- •Exhaustion
- •Lung Stim Liquescence 3026
- •Category V
- •NRV-Systemic
- •Lung Drops
- •Grass Pollen
- •Circulation
- •ANTI AGE Stress
- •Adrenalin (epinephrine in sodium chloride)
- •FCS HP
- •Bio Co-Enzyme Phase
- •BORR PLUS
- •FNG II
- •Allergen II
- •Lidocaine HCI
- •Adrenalin (Epinephrine)
- •Pollen-Weeds
- •Hyperactivity-Mental Focus
- •B07 Dprsn Antitox
- •N01 Protomer
- •Mold, Yeast and Dust
- •Allergy Care
- •Adrenalin Vials
- •Energy Complex
- •neffy
- •Metabolic Correction Blend
- •Tobacco
- •Resentment
- •Allerforce
- •Epipen
- •Lidocaine HCl AND Epinephrine
- •Epinephrine 0.3 Adults
- •Pollen and Dander Liquescence
- •Lung Liquescence
- •Tattoo
- •GUNA-Allergy T
- •Motivation
- •Histastat Pollen
- •Epipen JR
- •Hypercalm-Mental Focus
- •Thyroid-Adrenal
- •Outdoor Allergies
- •Weight Loss Support Plus Male Balance
- •Weight Loss Support Plus Thyroid
- •Anti Stress Formula
- •HP Axis
- •Mood Swings
- •Total FEM BAL
- •Brain Support
- •Circulation Drops 2013
- •Fever Flu Symptom Drops 2087
- •Weight Loss support Plus - GLP 1 Booster
- •Assist
- •Neuro T Support Liquescence
- •GUNA-Dizzy
- •Imucode
- •Shame
- •Endoplex F
- •Fatigue Fighter
- •Vitality
- •Total TRI-Estro
- •Anti-Stress Drops 2009
- •Opsin I 6014
- •Opsin II 6015
- •OHM Pituitarum Complex
- •Tree Pollen
- •Epinephrine 0.15 Pediatrics
- •Adrenal Liquescence
- •Thinnr Protocol
- •Stress / Fatigue
- •Focus
- •Bio Mood Phase
- •Cerebromax
- •Candid-Y
- •HBP
- •D-63
- •Total PRO-JES
- •Allergy Liquescence 3031
- •B02 Adrenal PEP
- •Epinephrine Pediatrics
- •Weight Loss Support Plus Immune Support
- •Thinnr Boost
- •Panacode
- •Recovatone
- •Appetite and Weight with P.H.A.T.
- •Grain and Wheat
- •GUNA Allergy
- •Adrenalin(R)
- •Lidocaine HCI AND Epinephrine
- •Epinephrine 1553
- •Adrenal-Tone
- •AppetiteGo
- •Stress II
- •Weight Loss Support Plus
- •Adrenal Tonic
- •911 Adrenal Burnout and Fatigue
- •Anti-Hives Drops 2004
- •Adrenal Liquescence 3001
- •B05 Gluco Balance
- •AllergiClear-M
- Current shortage
Epinephrine Bitartrate, Lidocaine Hydrochloride Injection
Shortage listed since February 22, 2012
Manufacturer reports: 1 unavailable, 1 limited, 2 available
- Current shortage
Bupivacaine Hydrochloride, Epinephrine Bitartrate Injection
Shortage listed since February 20, 2018
Manufacturer reports: 1 unavailable, 1 available
- to be discontinued
Epinephrine Injection
Shortage listed since November 7, 2025
Chemical Identity
Data Sources
- PubChem · compound 5816Retrieved 2026-04-07
- EPA TSCA InventoryRetrieved 2026-04-24
- FDA Drug ShortagesRetrieved 2026-10-04
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
epinephrine (CAS 51-43-4) https://chemicalindependence.com/chemical/51-43-4/ PubChem: 5816. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5816 EPA TSCA Inventory: CAS 51-43-4. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA Drug Shortages: CAS 51-43-4. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293790 for CAS 51-43-4. Reporting year: 2024. https://usatrade.census.gov/