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Procaine hydrochloride

Drug ingredient

CAS 51-05-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 51-05-8
1 HCl
US productionNot reported
Import value, 2024$503M
Top sourceChina 25%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292249 · basket

These shares come from HS customs code 292249, which covers 170 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 25%ChinaIN 17%IndiaSG 13%SingaporeIT 9%ItalyCH 7%Switzerland
5 FDA-registered drug labelers
Chongqing Southwest No.2 Pharmaceutical Factory Co., Ltd.
DARMERICA, LLC
ICROM SRL
Qingdao Biopeptek Co., Ltd.
Zhejiang Bamboo Pharmaceuticals Co.,Ltd

Why It Matters

Sectors
Health
Downstream UsesNot recorded
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS51-05-8
PubChem CID5795
DTXSIDDTXSID1044435
FormulaC13H21ClN2O2
Mol. Weight272.77 g/mol
SMILESCCN(CC)CCOC(=O)C1=CC=C(C=C1)N.Cl

Data Sources

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Brief citations

Procaine hydrochloride (CAS 51-05-8) https://chemicalindependence.com/chemical/51-05-8/ PubChem: 5795. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5795 EPA TSCA Inventory: CAS 51-05-8. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292249 for CAS 51-05-8. Reporting year: 2024. https://usatrade.census.gov/