Sodium Oxybate

Drug ingredient

CAS 502-85-2

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$81M

Top sourceChina 35%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291819 · basket

These shares come from HS customs code 291819, which covers 96 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 35%ChinaIN 34%IndiaIT 9%ItalyDE 9%GermanyJP 4%Japan

Switzerland
Ukraine
Colombia
Taiwan
Belgium
Israel
Sweden
Hungary
Ireland
Slovakia

15 FDA-registered drug labelers

Amneal Pharmaceuticals LLC

Avadel CNS Pharmaceuticals, LLC

Camber Pharmaceuticals, Inc.

Cambrex Charles City, Inc

Catalent Pharma Solutions, LLC

Chattem Chemicals, Inc.

Curia Missouri, Inc.

Curia New York, Inc.

Granules India Limited

Hikma Pharmaceuticals USA Inc.

Jazz Pharmaceuticals, Inc.

MERIBEL PHARMA PESSAC

Siegfried USA, LLC

Veranova, L.P.

XLCare Pharmaceuticals, Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 4 drug and cosmetic product listings (FDA).

•sodium oxybate
•Lumryz
•Xyrem
•Xywav

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No Shortage

Shortage History

Rows group FDA shortage filings by drug product. Each manufacturer makes its own FDA shortage filing, so one product can carry several reports at once: Available, Limited Availability, Unavailable or to be discontinued.

to be discontinued
Sodium Oxybate Solution
Shortage listed since December 29, 2025

See all current drug shortages

Chemical Identity

CAS502-85-2

PubChem CID23663870

DTXSIDDTXSID3048940

FormulaC4H7NaO3

Mol. Weight126.09 g/mol

SMILESC(CC(=O)[O-])CO.[Na+]

Data Sources

PubChem · compound 23663870Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA Drug ShortagesRetrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Sodium Oxybate (CAS 502-85-2) https://chemicalindependence.com/chemical/502-85-2/ PubChem: 23663870. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/23663870 EPA TSCA Inventory: CAS 502-85-2. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA Drug Shortages: CAS 502-85-2. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 291819 for CAS 502-85-2. Reporting year: 2024. https://usatrade.census.gov/