Nordihydroguaiaretic acid

CAS 500-38-9

Molecular structure of 500-38-9
US productionNot reported
Import value, 2024$72M
Top sourceIndia 30%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290729 · basket

These shares come from HS customs code 290729, which covers 82 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IN 30%IndiaDE 19%GermanyCN 16%ChinaJP 11%JapanIT 7%Italy

Why It Matters

No EPA sector or FDA product records name a use for this chemical.

Chemical Identity

CAS500-38-9
PubChem CIDNot recorded
DTXSIDDTXSID5022437
FormulaC18H22O4
Mol. Weight302.37 g/mol
SMILESCC(CC1=CC(O)=C(O)C=C1)C(C)CC1=CC=C(O)C(O)=C1

Data Sources

Brief citations

Nordihydroguaiaretic acid (CAS 500-38-9) https://chemicalindependence.com/chemical/500-38-9/ EPA CompTox (DSSTox): 500-38-9. Retrieved 2026-04-29. https://comptox.epa.gov/dashboard/chemical/details/DTXSID5022437 US Census international trade: HS 290729 for CAS 500-38-9. Reporting year: 2024. https://usatrade.census.gov/