phenylbutazone

Drug ingredient

CAS 50-33-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$597M

Top sourceSwitzerland 53%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293319 · basket

These shares come from HS customs code 293319, which covers 133 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CH 53%SwitzerlandDE 22%GermanyIN 14%IndiaCN 4%ChinaIT 3%Italy

Sweden
Ukraine
Taiwan
Spain
Canada
Portugal
Slovakia
New Zealand
Netherlands
Croatia
Latvia

9 FDA-registered drug labelers

Arene Life Sciences Private Limited

BioActive Nutritional, Inc

Energique, Inc.

Harman Finochem Limited

Kalchem International inc

Nantong Jinghua Pharmaceutical Co., Ltd.

Professional Compounding Centers of America dba PCCA

Supplement Clinic, LLC.

Zydus Lifesciences Limited

Why It Matters

Sectors

Health

Downstream Uses

Appears in 5 drug and cosmetic product listings (FDA).

•Chemstat
•Chemtox
•Hepatatox
•Lipotox
•Homeoplex D

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$0.22/gAaron Chemicals LLC

CountryHong Kong

Pack$108.00 / 500 g

Purity98%

Vendors24 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

23 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.23	500 g	98%
A2B Chem LLC	United States	$0.26	500 g	97%
AA BLOCKS	United States	$0.33	500 g	97%
Ambeed, Inc.	United States	$0.42	100 g	97%
AK Scientific Specialized	United States	$0.48	500 g	95%
AK Scientific, Inc.	United States	$0.66	500 g	98%
Sigma-Aldrich (Rush Stock)	Germany	$1.04	500 g	—
Sigma-Aldrich	Germany	$1.04	500 g	—
Angene International Limited	United States	$1.05	500 g	98%
Cayman Europe	Estonia	$1.81	50 g	99%
Fulfilled by Molport	Latvia	$3.00	1 g	95%
AstaTech (2 weeks)	United States	$9.60	5 g	95%
MedKoo Biosciences, Inc	United States	$14.00	25 g	98%
MedChemExpress MCE	Sweden	$30.01	5 g	99.82%
TargetMol Chemicals	China → United States	$38.00	1 g	99.93%
Molnova	China	$90.00	500 mg	99%
Specs	Netherlands	$804.65	1 g	90%
Maybridge, Ltd.	United Kingdom	$2414.30	100 mg	90%
Princeton BioMolecular Research (SC)	United States	$2900.00	100 mg	90%
Vitas M Chemical Limited	Hong Kong	$3170.00	100 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	98%
Key Organics Ltd.	United Kingdom	$6900.00	10 mg	97%
TimTec, LLC	United States	$9333.33	30 mg	90%

Chemical Identity

CAS50-33-9

PubChem CID4781

DTXSIDDTXSID9021136

FormulaC19H20N2O2

Mol. Weight308.4 g/mol

SMILESCCCCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3

Data Sources

PubChem · compound 4781Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

phenylbutazone (CAS 50-33-9) https://chemicalindependence.com/chemical/50-33-9/ PubChem: 4781. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/4781 EPA TSCA Inventory: CAS 50-33-9. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293319 for CAS 50-33-9. Reporting year: 2024. https://usatrade.census.gov/