Hydrocortisone

Drug ingredient

CAS 50-23-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 50-23-7
US productionNot reported
Import value, 2024$24M
Top sourceChina 67%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293721 · narrow

These shares come from HS customs code 293721, which covers 3 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 67%ChinaIN 25%IndiaIT 6%ItalyCA 1%Canada
217 FDA-registered drug labelers
A-S Medication Solutions
A2A Integrated Pharmaceuticals, LLC
Absolut Skin Incorporated
Acme United Corporation
Actavis Pharma, Inc.
AKRON PHARMA INC
Aldermed Inc.
Allegis Holdings LLC
ALLIED TRADE LINK LLC
Allure Labs Inc.
Alumier Labs
Amazon.com Services LLC
American Health Packaging
American Sales Company
AmerisourceBergen
Amneal Pharmaceuticals NY LLC
Amneal Pharmaceuticals of New York LLC
Ana-Cool, LLC
ANI Pharmaceuticals, Inc.
Army & Air Force Exchange Service
Asclemed USA Inc.
Aurobindo Pharma Limited
AvPAK
Balassa Laboratories Inc.
BalmRx, LLC
Bausch & Lomb Incoporated
Bausch & Lomb Incorporated
Bausch Health US LLC
Beiersdorf Inc
BJWC
BluePoint Laboratories
Bryant Ranch Prepack
Cardinal Health
Cardinal Health 110 dba LEADER
Chain Drug Marketing Association Inc.
Chartwell RX LLC
Chattem, Inc.
Cintas Corporation
Claridei Laboratories
Click Industries LLC
Clinical Formula LLC
Clinical Therapeutic Solutions
Cosette Pharmaceuticals, Inc.
Costco Wholesale Company
CP Skin Health Group, Inc.
Crane Safety LLC
Crown Laboratories
Curia Spain S.A.U.
CVS
CVS Health
CVS Pharmacy
CVS PHARMACY, INC
Derm Ventures LLC
DERMOSCRIBE PTY LTD
Deseret Biologicals, Inc.
DIRECT RX
DISCOUNT DRUG MART, INC.
DLC Laboratories, Inc
DMD Clinical Naturopathy
Dolgencorp Inc
Dolgencorp, LLC
DR. MARDER SKINCARE, LLC
Dynarex Corporation
E. Fougera & Co. a division of Fougera Pharmaceuticals Inc.
E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC
ELIXIR HEALTHCARE USA, LLC.
Encube Ethicals, Inc.
Energique, Inc.
Eton Pharmaceuticals, Inc.
EUROAPI France
Eywa Pharma Inc
Family Dollar Stores, Inc
FOURSTAR GROUP USA, INC.
FRED'S, INC.
Front Line Safety
FRONT PHARMACEUTICAL PLC
FSA Store Inc.
Galenova Inc
Geri-Care Pharmaceuticals, Corp
Guangdong Quadrant Ecological Technology Co., Ltd.
Guchutang Biotechnology (Longyan) Co., Ltd
H E B
Haleon US Holdings LLC
Hayden Caleel LLC
Henan Lihua Pharmaceutical Co Ltd
Henry Schein
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc
HyVee Inc
Insight Pharmaceuticals LLC
Isomedix Operations Inc
J&A Digital Inc.
Jiangsu Lianhuan Pharmaceutical Co.,Ltd.
Jiangxi He-Oumei Health Industry Co., Ltd.
Jiangxi Yudexi Pharmaceutical Co., LTD
Kalchem International inc
Kenvue Brands LLC
KMM Pharmaceuticals, LLC
Kramer Laboratories
Kroger Company
L. Perrigo Company
L'Oreal USA Products Inc.
LEADER
Leading Pharma, LLC
LETCO MEDICAL, LLC
Lovely Skin, Inc.
Major Pharmaceuticals
McKinley Resources Inc.
Medisca Inc.
Medline Industries, LP
Medrock Pharmacy LLC
Meijer Distribution Inc
Meijer, Inc.
Melaleuca, Inc.
Mericon Industries
Mission Pharmacal Company
MY IMPORTS USA LLC
Mylan Pharmaceuticals Inc.
Nantong Health & Beyond Hygienic Products Inc.
Natureplex, LLC
NeilMed Pharmaceuticals Inc
New World Imports, Inc
Nitro Quimica Corporation dba Alchemix A Nitro Quimica Corporation
NuCare Pharmaceuticals,Inc.
OAKTREE PRODUCTS, INC.
OL PHARMA TECH, LLC Drs PHARMACY
OL PHARMA TECH,LLC
Oncora Pharma, LLC
OPMX LLC
Padagis Israel Pharmaceuticals Ltd
Patheon Inc.
PD-Rx Pharmaceuticals, Inc.
Person and Covey
Pharma Source Direct, Inc.
Pharmacia & Upjohn Company LLC
Pharmacia and Upjohn Company LLC
PHARMACY CHOICE INC
Pharmacy Value Alliance LLC
Pharmadel LLC
Preferred Pharmaceuticals Inc.
Premier Brands of America, Inc.
Productos Zapotol Corp
Professional Complementary Health Formulas
Professional Compounding Centers of America
Proficient Rx LP
ProStat First Aid
ProStat First Aid LLC
Publix Super Markets Inc
PURETEK CORPORATION
Quest Products, LLC
RB Health (US) LLC
REMEDYREPACK INC.
RENU LABORATORIES, LLC
Rising Pharma Holdings, Inc.
Rite Aid
RITE AID CORPORATION
Rooftop Consumer Health, Inc.
Rugby Laboratories
Safetec of America, Inc.
Safeway
Salix Pharmaceuticals, Inc
Sam's West Inc
Sandoz Inc
Sanofi chimie
Saptalis Pharmaceuticals, LLC
Shandong Xinhua Pharmaceutical Company Limited
Sheffield Pharmaceuticals LLC
Shopko Stores Operating Co., LLC
Spa de Soleil
Spectrum Laboratory Products, Inc.
Sportpharm LLC
Sportpharm, Inc. dba Sportpharm
STRATEGIC SOURCING SERVICES LLC
Strides Pharma Inc.
Strides Pharma Science Limited
Sun Pharmaceutical Industries, Inc.
Symbiotec Pharmalab Limited
Tai Guk Pharm. Co., Ltd.
TARGET Corporation
The Great Atlantic & Pacific Tea Company
The Kroger Co
THERAPLEX, LLC
Thompson
Three Nations Corp
Tianjin Jinjin Pharmaceutical Co., Ltd.
Tianjin Tianyao Pharmaceuticals Co., Ltd.
Topco Associates LLC
Topiderm, Inc.
Trifecta Pharmaceuticals USA
TRIFECTA PHARMACEUTICALS USA LLC
Trifluent Pharma LLC
Twin Med LLC
Unifirst First Aid Corporation
Unipack LLC
Unishield
United Exchange Corp.
United Natural Foods, Inc. dba UNFI
Universal Distribution Center LLC
Veridian Healthcare
Vi Medical Products Inc.
VIADERMA DISTRIBUTION INC
VIVE HEALTH LLC
Wal-Mart Stores Inc
Walgreen Co.
Walgreen Company
Walgreens
Walgreens Co.
Walgreens Company
WalMart
Walmart Inc
Weeks & Leo Co., Inc.
Westlake Pharma LLC
Wildman Business Group
WINCO FOODS, LLC
Xenex Laboratories Inc
Zhejiang Guoyao Jingyue Aerosol Co., Ltd.
Zhejiang Jingwei Pharmaceutic Al Co., Ltd.
Zhejiang Xianju Pharmaceutical Co., Ltd.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 233 drug and cosmetic product listings (FDA).

  • •Hydrocortisone
  • •Alkindi Sprinkle
  • •Equate Cortisone
  • •Westlake Anti-itch
  • •Itch and Rash Cream
  • •Anti itch
  • •Anti-itch Paraben Free
  • •Maximum Strength Scalp Itch Relief Anti-itch
FDA Shortage Status
No Shortage
Shortage History
  • resolved

    Hydrocortisone Sodium Succinate Injection

    Shortage listed since March 24, 2023

See all current drug shortages

Chemical Identity

CAS50-23-7
PubChem CID5754
DTXSIDDTXSID7020714
FormulaC21H30O5
Mol. Weight362.5 g/mol
SMILESCC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O

Data Sources

Brief citations

Hydrocortisone (CAS 50-23-7) https://chemicalindependence.com/chemical/50-23-7/ PubChem: 5754. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5754 EPA TSCA Inventory: CAS 50-23-7. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA Drug Shortages: CAS 50-23-7. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293721 for CAS 50-23-7. Reporting year: 2024. https://usatrade.census.gov/