Flag of the United StatesAmerican Chemical Independence

Cortisone acetate

Drug ingredient

CAS 50-04-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 50-04-4
US productionNot reported
Import value, 2024$154M
Top sourceItaly 60%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293729 · basket

These shares come from HS customs code 293729, which covers 57 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IT 60%ItalyES 14%SpainCN 11%ChinaDE 6%GermanyAT 2%Austria
20 FDA-registered drug labelers
BioActive Nutritional
BioActive Nutritional, Inc
Boiron
Chartwell RX, LLC
Deseret Biologicals
Deseret Biologicals, Inc
Dr. Donna Restivo DC
Energetix Corporation
Energique, Inc.
EUROAPI FRANCE
Henan Lihua Pharmaceutical Co Ltd
King Bio Inc.
Natural Creations, Inc.
Nutritional Specialties, Inc.
Pro Weight Loss Inc.
Professional Complementary Health Formulas
Silver Star Brands
SLIMCELL, LLC
Supplement Clinic, LLC.
Zorex

Why It Matters

Sectors
Health
Downstream Uses

Appears in 44 drug and cosmetic product listings (FDA).

  • •Adrenal Support
  • •BP Reg
  • •Emotional Detox and Drainage
  • •Chemstat
  • •D3 Organ Support
  • •Anti-Inflammation Drops 2005
  • •Aller-Chord F
  • •Energize
Show all 44
  • •Immune Support
  • •Chemtox
  • •Neurotransmitter Pro
  • •Bio Glyoxal Phase
  • •Bio Tonsilla Phase
  • •Bio Galium Phase
  • •Glyreg
  • •Enviro I
  • •Cortisone aceticum
  • •Hormone Harmony
  • •Anti Stress Formula
  • •HP Axis
  • •Detox III
  • •Hepatatox
  • •Allergen I
  • •Relief-Tone
  • •Thyro Support
  • •Thinnr Protocol
  • •Stress / Fatigue
  • •Bio Mood Phase
  • •Universaltox
  • •Lipotox
  • •Hormone Balance
  • •Echinacea Combination 9222
  • •Selenium Combination 9245
  • •Male Stimulant
  • •Hormone Combination
  • •Cosmestat
  • •Appetite and Weight with P.H.A.T.
  • •Cortisone Acetate
  • •Homeoplex D
  • •Viril
  • •Pyrogenium Combination 9239
  • •AppetiteGo
  • •Stress II
  • •Grain and Soy Allergen Mix
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS50-04-4
PubChem CID5745
DTXSIDDTXSID0022858
FormulaC23H30O6
Mol. Weight402.5 g/mol
SMILESCC(=O)OCC(=O)C1(CCC2C1(CC(=O)C3C2CCC4=CC(=O)CCC34C)C)O

Data Sources

← Back to Dashboard← Back to Health

Brief citations

Cortisone acetate (CAS 50-04-4) https://chemicalindependence.com/chemical/50-04-4/ PubChem: 5745. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5745 FDA National Drug Code directory: CAS 50-04-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293729 for CAS 50-04-4. Reporting year: 2024. https://usatrade.census.gov/