Dexamethasone

Drug ingredientActive Shortage

CAS 50-02-2

This drug ingredient is in active FDA shortage. At least one manufacturer cannot meet demand.

Molecular structure of 50-02-2
US productionNot reported
Import value, 2024$1.1B
Top sourceSingapore 82%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293722 · basket

These shares come from HS customs code 293722, which covers 36 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
SG 82%SingaporeGB 15%United KingdomIT 2%Italy
69 FDA-registered drug labelers
A-S Medication Solutions
Advagen Pharma Ltd.
Advanced Rx of Tennessee, LLC
Advanced Rx Pharmacy of Tennessee, LLC
Allergan, Inc.
Alvogen Inc.
American Health Packaging
Amneal Pharmaceuticals NY LLC
Amneal Pharmaceuticals of New York LLC
ANI Pharmaceuticals, Inc.
Apotex Corp.
ARMAS PHARMACEUTICALS INC.
Bausch & Lomb Incorporated
Bionpharma Inc.,
Bryant Ranch Prepack
Cardinal Health 107, LLC
Chartwell RX, LLC
Curia Spain S.A.U.
Direct Rx
Doc Rx
Dr. Reddy's Laboratories, Inc.
Edenbridge Pharmaceuticals LLC.
EUROAPI FRANCE
EyePoint Pharmaceuticals US, Inc
Eyevance Pharmaceuticals, LLC
Farmabios S.p.A.
Galenova Inc
Golden State Medical Supply, Inc.
Guangdong Quadrant Ecological Technology Co., Ltd.
Harrow Eye, LLC
Hikma Pharmaceuticals USA, Inc.
Isomedix Operations Inc
Kanchan Healthcare Inc
Kesin Pharma Corporation
Larken Laboratories, Inc.
LETCO MEDICAL, LLC
Major Pharmaceuticals
Marlex Pharmaceuticals, Inc
Medisca Inc.
Nordic Pharma, Inc.
NorthStar Rx LLC
Northwind Health Company, LLC
Novartis Pharmaceuticals Corporation
NuCare Pharmaceutical, Inc.
NuCare Pharmaceuticals, Inc.
Ocular Therapeutix, Inc.
Padagis US LLC
PD-Rx Pharmaceuticals, Inc.
Pharmacia and Upjohn Company LLC
Prasco Laboratories
Preferred Pharmaceuticals Inc.
Professional Compounding Centers of America dba PCCA
Proficient Rx LP
Redpharm Drug
Redpharm Drug, Inc.
REMEDYREPACK INC.
Rising Pharma Holdings, Inc.
Sandoz Inc
Sportpharm LLC
Sportpharm, Inc. dba Sportpharm
Sun Pharmaceutical Industries, Inc.
Symbiotec Pharmalab Limited
SYMBIOTICA SPECIALITY INGREDIENTS SDN.BHD
Synergy Health AST, LLC
Tianjin Tianyao Pharmaceuticals Co.,Ltd.
Upsher-Smith Laboratories, LLC
Viona Pharmaceuticals Inc
zhejiang xianju pharmaceutical co., Ltd.
Zydus Lifesciences Limited

Why It Matters

Sectors
Health
Downstream Uses

Appears in 20 drug and cosmetic product listings (FDA).

  • •Dexamethasone
  • •Tobramycin AND Dexamethasone
  • •Neomycin and Polymyxin B Sulfates and Dexamethasone
  • •Neomycin Polymyxin B Sulfates and Dexamethasone
  • •Ciprofloxacin and dexamethasone
  • •Tobradex ST
  • •Ozurdex
  • •Dextenza
FDA Shortage Status
Active Shortage
Shortage History
  • Current shortage

    Dexamethasone Sodium Phosphate Injection

    Shortage listed since February 8, 2019

    Manufacturer reports: 1 unavailable, 1 available

See all current drug shortages

Vendor Pricing

$2.26/gManchester Organics
CountryUnited Kingdom
Pack$225.61 / 100 g
Purity98%
Vendors27 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS50-02-2
PubChem CID5743
DTXSIDDTXSID3020384
FormulaC22H29FO5
Mol. Weight392.5 g/mol
SMILESCC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C

Data Sources

Brief citations

Dexamethasone (CAS 50-02-2) https://chemicalindependence.com/chemical/50-02-2/ PubChem: 5743. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5743 EPA TSCA Inventory: CAS 50-02-2. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA Drug Shortages: CAS 50-02-2. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293722 for CAS 50-02-2. Reporting year: 2024. https://usatrade.census.gov/