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aconitic acid

Drug ingredient

CAS 499-12-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 499-12-7
US productionNot reported
Import value, 2024$139M
Top sourceChina 67%

EPA lists this chemical as inactive, meaning no company reported making, importing or processing it in the US from 2006 to 2016.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291719 · basket

These shares come from HS customs code 291719, which covers 176 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 67%ChinaCA 13%CanadaAT 4%AustriaIN 4%IndiaJP 4%Japan
3 FDA-registered drug labelers
Deseret Biologicals, Inc.
Energique, Inc.
Nutritional Specialties, Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

  • •Bio Co Enzyme Phase
  • •Lungex II
  • •Metab
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS499-12-7
PubChem CID309
DTXSIDDTXSID9060102
FormulaC6H6O6
Mol. Weight174.11 g/mol
SMILESC(C(=CC(=O)O)C(=O)O)C(=O)O

Data Sources

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Brief citations

aconitic acid (CAS 499-12-7) https://chemicalindependence.com/chemical/499-12-7/ PubChem: 309. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/309 EPA TSCA Inventory: CAS 499-12-7. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 291719 for CAS 499-12-7. Reporting year: 2024. https://usatrade.census.gov/