Lurbinectedin

Drug ingredient

CAS 497871-47-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$7M

Top sourceIndia 45%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293980 · basket

These shares come from HS customs code 293980, which covers 3 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IN 45%IndiaCH 15%SwitzerlandCN 15%ChinaDE 10%GermanyNZ 9%New Zealand

Canada
Estonia
Spain

6 FDA-registered drug labelers

Apicore Pharmaceuticals Private Limited

Bamboo US Bidco LCC

GP PHARM SA

Jazz Pharmaceuticals, Inc.

MSN Laboratories Private Limited

Wisdom Pharmaceutical Co.,Ltd

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Zepzelca

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS497871-47-3

PubChem CID57327016

DTXSIDDTXSID30198065

FormulaC41H44N4O10S

Mol. Weight784.9 g/mol

SMILESCC1=CC2=C(C3C4C5C6=C(C(=C7C(=C6C(N4C(C(C2)N3C)O)COC(=O)C8(CS5)C9=C(CCN8)C2=C(N9)C=CC(=C2)OC)OCO7)C)OC(=O)C)C(=C1OC)O

Data Sources

PubChem · compound 57327016Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Lurbinectedin (CAS 497871-47-3) https://chemicalindependence.com/chemical/497871-47-3/ PubChem: 57327016. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/57327016 FDA National Drug Code directory: CAS 497871-47-3. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293980 for CAS 497871-47-3. Reporting year: 2024. https://usatrade.census.gov/