Givinostat

Drug ingredient

CAS 497833-27-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$191M

Top sourceSwitzerland 35%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292800 · basket

These shares come from HS customs code 292800, which covers 112 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CH 35%SwitzerlandIT 28%ItalyCN 12%ChinaIN 6%IndiaJP 6%Japan

Canada
Spain
Mexico
Netherlands
Poland
Malta
Norway
Ukraine
Belgium
Israel
Czech Republic
Austria
Indonesia
United Arab Emirates
Brazil
Lithuania

1 FDA-registered drug labeler

Italfarmaco SPA

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Duvyzat

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$1650.00/gCombi-Blocks (back-ordered)

CountryUnited States

Pack$1650.00 / 1 g

Purity95%

Vendors17 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

16 more vendors

Vendor	Country	$/g	Pack	Purity
BLD Pharmatech Ltd.	China	$1908.00	1 g	99%
Aaron Chemicals LLC	Hong Kong	$2252.00	250 mg	99%
Angene Chemical	China → Hong Kong	$2584.00	250 mg	99%
A2B Chem LLC	United States	$2650.00	100 mg	99%
Ambeed, Inc.	United States	$2828.00	250 mg	99%
AA BLOCKS	United States	$2940.00	100 mg	99%
BLD Pharmatech Co., Limited	United States	$3720.00	100 mg	99%
Excenen Pharmatech Co., Ltd	China	$4800.00	250 mg	98%
TargetMol Chemicals	China → United States	$6960.00	100 mg	98.56%
TargetMol Chemicals US	United States	$9280.00	50 mg	98.56%
MedChemExpress MCE	Sweden	$11119.90	100 mg	98.67%
TargetMol Chemicals EU	Austria	$11600.00	25 mg	98.56%
AstaTech, Inc	United States	$12320.00	50 mg	95%
Angene International Limited	United States	$20320.00	50 mg	95%
Molnova	China	$28900.00	10 mg	99%
MedKoo Biosciences, Inc	United States	$30000.00	25 mg	98%

Chemical Identity

CAS497833-27-9

PubChem CID9804992

DTXSIDDTXSID70198049

FormulaC24H27N3O4

Mol. Weight421.5 g/mol

SMILESCCN(CC)CC1=CC2=C(C=C1)C=C(C=C2)COC(=O)NC3=CC=C(C=C3)C(=O)NO

Data Sources

PubChem · compound 9804992Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

← Back to Dashboard ← Back to Health

Brief citations

Givinostat (CAS 497833-27-9) https://chemicalindependence.com/chemical/497833-27-9/ PubChem: 9804992. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/9804992 FDA National Drug Code directory: CAS 497833-27-9. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292800 for CAS 497833-27-9. Reporting year: 2024. https://usatrade.census.gov/