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Arbutin

Drug ingredient

CAS 497-76-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 497-76-7
US productionNot reported
Import value, 2024$296M
Top sourceChina 71%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293890 · basket

These shares come from HS customs code 293890, which covers 25 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 71%ChinaMY 11%MalaysiaBR 3%BrazilKR 2%South KoreaCL 2%Chile
3 FDA-registered drug labelers
Guangzhou Kadiya Biotechnology Co., Ltd.
Guangzhou Yanxi Biotechnology Co., Ltd
LAON COMMERCE co ltd

Why It Matters

Sectors
Health
Downstream Uses

Appears in 5 drug and cosmetic product listings (FDA).

  • •Reoganic EX Whitening Pore Care Deodorant
  • •remove black milk cream
  • •CRSoap
  • •CR whitening Cream
  • •dark knuckles eraser pen
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS497-76-7
PubChem CID440936
DTXSIDDTXSID7040152
FormulaC12H16O7
Mol. Weight272.25 g/mol
SMILESC1=CC(=CC=C1O)OC2C(C(C(C(O2)CO)O)O)O

Data Sources

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Brief citations

Arbutin (CAS 497-76-7) https://chemicalindependence.com/chemical/497-76-7/ PubChem: 440936. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/440936 FDA National Drug Code directory: CAS 497-76-7. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293890 for CAS 497-76-7. Reporting year: 2024. https://usatrade.census.gov/