3-Methyl-4,6-di-tert-butylphenol

CAS 497-39-2

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$33M

Import volumeZero

Top sourceGermany 29%

At least one company claimed its 2019 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2019. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290719 · basket

EPA reports by year

2023: US production Not published · Imports Not published
2019: US production Confidential · Imports Zero

These shares come from HS customs code 290719, which covers 116 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

DE 29%GermanyIN 26%IndiaCN 19%ChinaIT 9%ItalyCH 5%Switzerland

Mexico
Poland
South Korea
Canada
Russia
Ukraine
Hong Kong
Malaysia
United Kingdom

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Sasol (Usa)

Why It Matters

Sectors

Energy

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in Cyclic Crude and Intermediate Manufacturing (90%)Processing as a reactant

Vendor Pricing

$0.11/gAaron Chemicals LLC

CountryHong Kong

Pack$54.00 / 500 g

Purity98%

Vendors15 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

14 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.13	500 g	98%
A2B Chem LLC	United States	$0.18	500 g	97%
BLD Pharmatech GmbH	Germany	$0.20	1 kg	96%
BLD Pharmatech Ltd.	China	$0.20	1 kg	96%
AA BLOCKS	United States	$0.23	500 g	96%
Combi-Blocks, Inc.	United States	$0.25	1 kg	97%
Ambeed, Inc.	United States	$0.26	500 g	96%
BLD Pharmatech Co., Limited	United States	$0.38	100 g	96%
AstaTech (2 weeks)	United States	$5.12	25 g	95%
AK Scientific Specialized	United States	$6.00	25 g	95%
AK Scientific, Inc.	United States	$8.24	25 g	96%
Angene International Limited	United States	$14.08	25 g	96%
TargetMol Chemicals	China → United States	$450.00	100 mg	98.88%
Angene	China → Hong Kong	$4266.67	30 mg	98%

Chemical Identity

CAS497-39-2

PubChem CID10346

DTXSIDDTXSID1041502

FormulaC15H24O

Mol. Weight220.35 g/mol

SMILESCC1=CC(=C(C=C1C(C)(C)C)C(C)(C)C)O

Data Sources

EPA CompTox (DSSTox) · DTXSID1041502Retrieved 2026-04-06
PubChem · compound 10346Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

3-Methyl-4,6-di-tert-butylphenol (CAS 497-39-2) https://chemicalindependence.com/chemical/497-39-2/ EPA CompTox (DSSTox): DTXSID1041502. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID1041502 PubChem: 10346. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/10346 EPA Chemical Data Reporting: 497-39-2. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 497-39-2. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290719 for CAS 497-39-2. Reporting year: 2024. https://usatrade.census.gov/