Calcium cis-1,2-cyclohexanedicarboxylate

CAS 491589-22-1

U.S. production volumes are classified as confidential business information.

Molecular structure of 491589-22-1 — 1 Ca²⁺

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$37M

Top sourceChina 25%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291720 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 291720, which covers 42 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 25%ChinaIT 21%ItalyJP 21%JapanDE 14%GermanyIN 9%India

Ukraine
South Africa
Malaysia
Netherlands
Mexico
United Kingdom
Switzerland
Latvia
Canada

EPA-registered importers (3)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Government Of Abu Dhabi · AE United Arab Emirates

Dow Chemical

Nc Holdings Usa

Why It Matters

Sectors

Metals & MiningPlastics & RubberCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 3 sectors as 1 functional role.

•Crystal growth modifiers (nucleating agents) in Plastics Material and Resin Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Crystal growth modifiers (nucleating agents) in Plastics Product Manufacturing (100%)Processing—incorporation into article
•Crystal growth modifiers (nucleating agents) in Other (0%)Processing—repackaging

Chemical Identity

CAS491589-22-1

PubChem CID67202838

DTXSIDDTXSID30197699

FormulaC8H10CaO4

Mol. Weight210.24 g/mol

SMILESC1CCC(C(C1)C(=O)[O-])C(=O)[O-].[Ca+2]

Data Sources

EPA CompTox (DSSTox) · DTXSID30197699Retrieved 2026-04-06
PubChem · compound 67202838Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Calcium cis-1,2-cyclohexanedicarboxylate (CAS 491589-22-1) https://chemicalindependence.com/chemical/491589-22-1/ EPA CompTox (DSSTox): DTXSID30197699. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID30197699 PubChem: 67202838. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/67202838 EPA Chemical Data Reporting: 491589-22-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 491589-22-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 291720 for CAS 491589-22-1. Reporting year: 2024. https://usatrade.census.gov/